Transforming growth factor
hideTransforming growth factor (sometimes referred to as Tumor growth factor, or TGF) is used to describe two classes of polypeptide growth factors, TGFα and TGFβ.
The name "Transforming Growth Factor" is somewhat arbitrary, since the two classes of TGFs are not structurally or genetically related to one another, and they act through different receptor mechanisms. Furthermore, they do not always induce cellular transformation, and are not the only growth factors that induce cellular transformation.
For more information about Transforming growth factor, read the full article at
Wikipedia.
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News tagged with tumor growth
Possible ovarian cancer treatment target identified
21 hours ago |
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A multi-institutional study has identified a potential personalized treatment target for the most common form of ovarian cancer. In the December 8 issue of Cancer Cell, the research team describes finding that a gene called ...
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Omega-3 fatty acids may reduce risk of colon cancer
Dec 08, 2009 |
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Long-chain omega-3 fatty acids, primarily found in fish and seafood, may have a role in colorectal cancer prevention, according to results presented at the American Association for Cancer Research Frontiers in Cancer Prevention ...
Spices halt growth of breast stem cells, study finds
Dec 07, 2009 |
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A new study finds that compounds derived from the spices turmeric and pepper could help prevent breast cancer by limiting the growth of stem cells, the small number of cells that fuel a tumor's growth.
New hope for diagnosis and treatment of intractable pediatric brain tumors
Dec 07, 2009 |
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Scientists have discovered oncogenes capable of driving growth of normal human brain stem cells in a highly malignant pediatric brain tumor. The research, published by Cell Press in the December issue of the journal Cancer Ce ...
New understanding of how to prevent destruction of a tumor suppressor
Dec 07, 2009 |
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Researchers from the Indiana University School of Medicine and colleagues at the University of Texas Southwestern and Case Western University have determined how the protein Mdm2, which is elevated in late-stage ...
Tiny RNA has big impact on lung cancer tumors
Dec 07, 2009 |
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Researchers from Yale University and Mirna Therapeutics, Inc., reversed the growth of lung tumors in mice using a naturally occurring tumor suppressor microRNA. The study reveals that a tiny bit of RNA may one day play a ...
'Live' imaging reveals breast cancer cells' transition to metastasis
Dec 06, 2009 |
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The spread, or metastasis, of individual breast cancer cells from the main tumor into the blood circulation to the lungs and other body tissues and organs is under the control of a growth factor abbreviated TGFb, according ...
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