Transforming growth factor
hideTransforming growth factor (sometimes referred to as Tumor growth factor, or TGF) is used to describe two classes of polypeptide growth factors, TGFα and TGFβ.
The name "Transforming Growth Factor" is somewhat arbitrary, since the two classes of TGFs are not structurally or genetically related to one another, and they act through different receptor mechanisms. Furthermore, they do not always induce cellular transformation, and are not the only growth factors that induce cellular transformation.
For more information about Transforming growth factor, read the full article at
Wikipedia.
This text uses material from Wikipedia and is available under the GNU Free Documentation License.
News tagged with tumor growth
Laser therapy can aggravate skin cancer
Nov 20, 2009 |
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High irradiances of low-level laser therapy (LLLT) should not be used over melanomas. Researchers writing in the open access journal BMC Cancer studied the pain relieving, anti-inflammatory 'cold laser', finding that it cau ...
Wistar researchers show targeting 'normal' cells in tumors slows growth
Nov 16, 2009 |
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Targeting the normal cells that surround cancer cells within and around a tumor is a strategy that could greatly increase the effectiveness of traditional anti-cancer treatments, say researchers at The Wistar Institute.
Researchers 'notch' a victory toward new kind of cancer drug
Nov 11, 2009 |
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(PhysOrg.com) -- Scientists have devised an innovative way to disarm a key protein considered to be "undruggable," meaning that all previous efforts to develop a drug against it have failed. Their discovery, published in ...
Nanoparticles for gene therapy improve
Nanotechnology / Bio & Medicine
Nov 06, 2009 |
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(PhysOrg.com) -- About five years ago, Professor Janet Sawicki at the Lankenau Institute in Pennsylvania read an article about nanoparticles developed by MIT's Robert Langer for gene therapy, the insertion ...
Cancer research gets physical
Oct 27, 2009 |
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(PhysOrg.com) -- Cancer research has traditionally been the realm of biologists, and, more recently, engineers. Now, physicists are getting in on the action.
Protein is linked to lung cancer development
Oct 22, 2009 |
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(PhysOrg.com) -- A protein that normally helps defend cells from infection can play a critical role in the development of lung cancer, according to MIT cancer biologists.
Lack of Social Interaction Affects Health Outcomes of Breast Cancer
Oct 19, 2009 |
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(PhysOrg.com) -- Social environment can play an important role in the biology of disease, including breast cancer, and lead to significant differences in health outcome, according to results of a study published in Cancer Pr ...
Using RNAi-based technique, scientists find new tumor suppressor genes in lymphoma
Oct 13, 2009 |
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Researchers from Cold Spring Harbor Laboratory (CSHL) have uncovered a large, new cache of genes that act as built-in barriers against cancer. Known as tumor suppressors, the newly identified genes and the insight that they ...
Prostate Tumors Can Change the Function of Immune Cells in Mice
Oct 07, 2009 |
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(PhysOrg.com) -- Researchers have discovered that prostate tumors in mice can cause immune cells known as CD8+ T cells to change their function from cells that have antitumor activity to cells that suppress immune responses. ...
Diabetes drug kills cancer stem cells in combination treatment in mice
Sep 14, 2009 |
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In a one-two punch, a familiar diabetes drug reduced tumors faster and prolonged remission in mice longer than chemotherapy alone by targeting cancer stem cells, Harvard Medical School researchers reported in the September ...
Researchers identify potential target for metastatic cancer
Aug 10, 2009 |
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The deadliest part of the cancer process, metastasis, appears to rely on help from macrophages, potent immune system cells that usually defend vigorously against disease, researchers at Albert Einstein College ...
Nanoparticle-delivered 'suicide' genes slowed ovarian tumor growth (w/ Video)
Jul 30, 2009 |
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Nanoparticle delivery of diphtheria toxin-encoding DNA selectively expressed in ovarian cancer cells reduced the burden of ovarian tumors in mice, and researchers expect this therapy could be tested in humans within 18 to ...
Trojan horse for ovarian cancer -- nanoparticles turn immune system soldiers against tumor cells
Nanotechnology / Bio & Medicine
Jul 15, 2009 |
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In a feat of trickery, Dartmouth Medical School immunologists have devised a Trojan horse to help overcome ovarian cancer, unleashing a surprise killer in the surroundings of a hard-to-treat tumor.
Fluorescent probes may permit monitoring of chemotherapy effectiveness
Jul 13, 2009 |
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Going out like a brilliant flame is one way to get attention. If physicians could watch tumor cells committing a form of programmed suicide called apoptosis, a desired effect of workhorse cancer treatments such as chemotherapy ...
Scientists link elevated insulin to increased breast cancer risk
Jul 09, 2009 |
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Elevated insulin levels in the blood appear to raise the risk of breast cancer in postmenopausal women, according to researchers at Albert Einstein College of Medicine of Yeshiva University. Their findings are published in ...
