Transforming growth factor
hideTransforming growth factor (sometimes referred to as Tumor growth factor, or TGF) is used to describe two classes of polypeptide growth factors, TGFα and TGFβ.
The name "Transforming Growth Factor" is somewhat arbitrary, since the two classes of TGFs are not structurally or genetically related to one another, and they act through different receptor mechanisms. Furthermore, they do not always induce cellular transformation, and are not the only growth factors that induce cellular transformation.
For more information about Transforming growth factor, read the full article at
Wikipedia.
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News tagged with tumor growth
Possible ovarian cancer treatment target identified
Dec 08, 2009 |
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A multi-institutional study has identified a potential personalized treatment target for the most common form of ovarian cancer. In the December 8 issue of Cancer Cell, the research team describes finding that a gene called ...
Nanoparticles for gene therapy improve
Nanotechnology / Bio & Medicine
Nov 06, 2009 |
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(PhysOrg.com) -- About five years ago, Professor Janet Sawicki at the Lankenau Institute in Pennsylvania read an article about nanoparticles developed by MIT's Robert Langer for gene therapy, the insertion ...
Scientists engineer new type of vaccination that provides instant immunity
Mar 02, 2009 |
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The experiments, thus far performed only in mice, appear to overcome a major drawback of vaccinations - the lag time of days, or even weeks, that it normally takes for immunity to build against a pathogen. This new method ...
Researchers 'notch' a victory toward new kind of cancer drug
Nov 11, 2009 |
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(PhysOrg.com) -- Scientists have devised an innovative way to disarm a key protein considered to be "undruggable," meaning that all previous efforts to develop a drug against it have failed. Their discovery, published in ...
Nanoparticle-delivered 'suicide' genes slowed ovarian tumor growth (w/ Video)
Jul 30, 2009 |
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Nanoparticle delivery of diphtheria toxin-encoding DNA selectively expressed in ovarian cancer cells reduced the burden of ovarian tumors in mice, and researchers expect this therapy could be tested in humans within 18 to ...
Laser therapy can aggravate skin cancer
Nov 20, 2009 |
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High irradiances of low-level laser therapy (LLLT) should not be used over melanomas. Researchers writing in the open access journal BMC Cancer studied the pain relieving, anti-inflammatory 'cold laser', finding that it cau ...
Diabetes drug kills cancer stem cells in combination treatment in mice
Sep 14, 2009 |
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In a one-two punch, a familiar diabetes drug reduced tumors faster and prolonged remission in mice longer than chemotherapy alone by targeting cancer stem cells, Harvard Medical School researchers reported in the September ...
Wistar researchers show targeting 'normal' cells in tumors slows growth
Nov 16, 2009 |
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Targeting the normal cells that surround cancer cells within and around a tumor is a strategy that could greatly increase the effectiveness of traditional anti-cancer treatments, say researchers at The Wistar Institute.
Protein is linked to lung cancer development
Oct 22, 2009 |
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(PhysOrg.com) -- A protein that normally helps defend cells from infection can play a critical role in the development of lung cancer, according to MIT cancer biologists.
Trojan horse for ovarian cancer -- nanoparticles turn immune system soldiers against tumor cells
Nanotechnology / Bio & Medicine
Jul 15, 2009 |
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In a feat of trickery, Dartmouth Medical School immunologists have devised a Trojan horse to help overcome ovarian cancer, unleashing a surprise killer in the surroundings of a hard-to-treat tumor.
Using RNAi-based technique, scientists find new tumor suppressor genes in lymphoma
Oct 13, 2009 |
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Researchers from Cold Spring Harbor Laboratory (CSHL) have uncovered a large, new cache of genes that act as built-in barriers against cancer. Known as tumor suppressors, the newly identified genes and the insight that they ...
Grapefruit juice boosts drug's anti-cancer effects
Apr 20, 2009 |
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In a small, early clinical trial, researchers at the University of Chicago Medical Center have found that combining eight ounces of grapefruit juice with the drug rapamycin can increase drug levels, allowing lower doses of ...
Targeting breast cancer stem cells in mice
Jun 02, 2009 |
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Cancer develops when cells known as cancer stem cells begin to divide in an uncontrolled manner. Researchers from the University of Michigan Comprehensive Cancer Center have identified roles for the gene PTEN, ...
Carbohydrate restriction may slow prostate tumor growth
May 26, 2009 |
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Restricting carbohydrates, regardless of weight loss, appears to slow the growth of prostate tumors, according to an animal study being published this week by researchers in the Duke Prostate Center.
Estrogen found to increase growth of the most common childhood brain tumor
Feb 17, 2009 |
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University of Cincinnati (UC) researchers have discovered that estrogen receptors are present in medulloblastoma—the most common type of pediatric brain tumor—leading them to believe that anti-estrogen drug treatments may ...
