Transforming growth factor
hideTransforming growth factor (sometimes referred to as Tumor growth factor, or TGF) is used to describe two classes of polypeptide growth factors, TGFα and TGFβ.
The name "Transforming Growth Factor" is somewhat arbitrary, since the two classes of TGFs are not structurally or genetically related to one another, and they act through different receptor mechanisms. Furthermore, they do not always induce cellular transformation, and are not the only growth factors that induce cellular transformation.
For more information about Transforming growth factor, read the full article at
Wikipedia.
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News tagged with tumor growth
Laser therapy can aggravate skin cancer
Nov 20, 2009 |
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High irradiances of low-level laser therapy (LLLT) should not be used over melanomas. Researchers writing in the open access journal BMC Cancer studied the pain relieving, anti-inflammatory 'cold laser', finding that it cau ...
Possible ovarian cancer treatment target identified
Dec 08, 2009 |
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A multi-institutional study has identified a potential personalized treatment target for the most common form of ovarian cancer. In the December 8 issue of Cancer Cell, the research team describes finding that a gene called ...
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Brain surgery evolves to destroy rogue blood vessels
6 hours ago |
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(PhysOrg.com) -- Over three decades, a world-recognized medical team at UC San Diego Medical Center has spurred the evolution of a complex surgery to destroy dangerous clusters of arteries and veins in the brain. Integrating ...
Stem-cell activators switch function, repress mature cells
10 hours ago |
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In a developing animal, stem cells proliferate and differentiate to form the organs needed for life. A new study shows how a crucial step in this process happens and how a reversal of that step contributes to cancer.
Targeting brain cancer cell metabolism may provide new treatment
Dec 15, 2009 |
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Inhibiting fatty acid synthesis in brain cancer cells may offer a new option to treat about 50 percent of deadly glioblastomas that are driven by amplified signaling of the epidermal growth factor receptor (EGFR), according ...
New suppressor of common liver cancer
Dec 15, 2009 |
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Tumor suppressor genes make proteins that help control cell growth. Mutations in these genes that generate nonfunctional proteins can contribute to tumor development and progression. One of the most well-known tumor suppressor ...
New protein key for cell proliferation identified
Dec 14, 2009 |
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(PhysOrg.com) -- Researchers at McGill University have identified a protein that plays a key role in cell proliferation and is likely to promote cancer development. The work may lead to the development of new diagnostic tools ...
Scientists crack mystery of protein's dual function
Dec 13, 2009 |
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Researchers at The Scripps Research Institute have solved a 10-year-old mystery of how a single protein from an ancient family of enzymes can have two completely distinct roles in the body. In addition to providing guidance ...
Antibody-guided drug shows encouraging activity in metastatic breast cancer
Dec 12, 2009 |
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A new antibody-drug compound shrank or halted the growth of metastatic breast tumors in almost half of a group of patients whose HER2-positive cancer had become resistant to standard therapies, according to early data from ...
Landmark study confirms chemotherapy benefit in breast cancer patients
Dec 11, 2009 |
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Chemotherapy generally improves survival in postmenopausal breast cancer patients, according to a landmark study led by Dr. Kathy Albain of Loyola University Health System.
Decline of hormone therapy decreases breast cancer cases, analysis finds
Dec 09, 2009 |
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The declining use of hormone therapy among women has led to 6,000 fewer invasive breast cancer cases a year, according to an analysis by researchers at the University of Wisconsin-Madison. The research quantifies and advances ...
Study Describes Novel Model of Skin Cancer
Dec 09, 2009 |
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(PhysOrg.com) -- Scientists at the University of Pennsylvania School of Medicine have developed a new model of skin cancer based on the knowledge that a common cancer-related molecule called Src kinase is ...
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