Related topics: cancer , breast cancer , tumor
Transforming growth factor
hideTransforming growth factor (sometimes referred to as Tumor growth factor, or TGF) is used to describe two classes of polypeptide growth factors, TGFα and TGFβ.
The name "Transforming Growth Factor" is somewhat arbitrary, since the two classes of TGFs are not structurally or genetically related to one another, and they act through different receptor mechanisms. Furthermore, they do not always induce cellular transformation, and are not the only growth factors that induce cellular transformation.
For more information about Transforming growth factor, read the full article at
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News tagged with tumor growth
Knockdown of E2F1 reduces invasive potential of melanoma cells
Dec 23, 2009 |
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Inhibition of transcription factor E2F1 reduced epidermal growth factor receptor (EGFR) expression and reduced the invasive potential but not proliferation of metastatic melanoma cells, according to a brief communication ...
'Self-seeding' of cancer cells may play a critical role in tumor progression
17 hours ago |
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Cancer progression is commonly thought of as a process involving the growth of a primary tumor followed by metastasis, in which cancer cells leave the primary tumor and spread to distant organs. A new study by researchers ...
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Protein link may be key to new treatment for aggressive brain tumor
Dec 22, 2009 |
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Biomedical researchers at the University of Central Florida have found a protein that could hold the key to treating one of the most common and aggressive brain tumors in adults.
Metastasis formation revealed in detail and real time
Dec 20, 2009 |
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Up to 25% of cancer patients develop metastases in the brain - often long after successful treatment of the primary tumor. In almost all such cases, the prognosis is poor. The mechanisms responsible for the appearance of ...
Research yields new agent for some drug-resistant non-small cell lung cancers
Dec 23, 2009 |
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The ability to make, test, and map the atomic structure of new anti-cancer agents has enabled a team of Dana-Farber Cancer Institute scientists to discover a compound capable of halting a common type of drug-resistant ...
Figitumumab has anti-tumor activity in Ewing's sarcoma
Dec 23, 2009 |
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A preliminary study of the anticancer drug figitumumab has found that it has antitumour activity in Ewing's sarcoma—a cancer which affects mainly teenage boys. The results have led to the drug's progression to a Phase 2 trial ...
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