Related topics: cancer , breast cancer , tumor
Transforming growth factor
hideTransforming growth factor (sometimes referred to as Tumor growth factor, or TGF) is used to describe two classes of polypeptide growth factors, TGFα and TGFβ.
The name "Transforming Growth Factor" is somewhat arbitrary, since the two classes of TGFs are not structurally or genetically related to one another, and they act through different receptor mechanisms. Furthermore, they do not always induce cellular transformation, and are not the only growth factors that induce cellular transformation.
For more information about Transforming growth factor, read the full article at
Wikipedia.
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News tagged with tumor growth
'Self-seeding' of cancer cells may play a critical role in tumor progression
Dec 24, 2009 |
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Cancer progression is commonly thought of as a process involving the growth of a primary tumor followed by metastasis, in which cancer cells leave the primary tumor and spread to distant organs. A new study by researchers ...
Knockdown of E2F1 reduces invasive potential of melanoma cells
Dec 23, 2009 |
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Inhibition of transcription factor E2F1 reduced epidermal growth factor receptor (EGFR) expression and reduced the invasive potential but not proliferation of metastatic melanoma cells, according to a brief communication ...
Possible ovarian cancer treatment target identified
Dec 08, 2009 |
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A multi-institutional study has identified a potential personalized treatment target for the most common form of ovarian cancer. In the December 8 issue of Cancer Cell, the research team describes finding that a gene called ...
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Figitumumab has anti-tumor activity in Ewing's sarcoma
Dec 23, 2009 |
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A preliminary study of the anticancer drug figitumumab has found that it has antitumour activity in Ewing's sarcoma—a cancer which affects mainly teenage boys. The results have led to the drug's progression to a Phase 2 trial ...
Research yields new agent for some drug-resistant non-small cell lung cancers
Dec 23, 2009 |
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The ability to make, test, and map the atomic structure of new anti-cancer agents has enabled a team of Dana-Farber Cancer Institute scientists to discover a compound capable of halting a common type of drug-resistant ...
Protein link may be key to new treatment for aggressive brain tumor
Dec 22, 2009 |
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Biomedical researchers at the University of Central Florida have found a protein that could hold the key to treating one of the most common and aggressive brain tumors in adults.
Metastasis formation revealed in detail and real time
Dec 20, 2009 |
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Up to 25% of cancer patients develop metastases in the brain - often long after successful treatment of the primary tumor. In almost all such cases, the prognosis is poor. The mechanisms responsible for the appearance of ...
Brain surgery evolves to destroy rogue blood vessels
Dec 16, 2009 |
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(PhysOrg.com) -- Over three decades, a world-recognized medical team at UC San Diego Medical Center has spurred the evolution of a complex surgery to destroy dangerous clusters of arteries and veins in the brain. Integrating ...
Stem-cell activators switch function, repress mature cells
Dec 16, 2009 |
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In a developing animal, stem cells proliferate and differentiate to form the organs needed for life. A new study shows how a crucial step in this process happens and how a reversal of that step contributes to cancer.
Targeting brain cancer cell metabolism may provide new treatment
Dec 15, 2009 |
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Inhibiting fatty acid synthesis in brain cancer cells may offer a new option to treat about 50 percent of deadly glioblastomas that are driven by amplified signaling of the epidermal growth factor receptor (EGFR), according ...
New suppressor of common liver cancer
Dec 15, 2009 |
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Tumor suppressor genes make proteins that help control cell growth. Mutations in these genes that generate nonfunctional proteins can contribute to tumor development and progression. One of the most well-known tumor suppressor ...
New protein key for cell proliferation identified
Dec 14, 2009 |
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(PhysOrg.com) -- Researchers at McGill University have identified a protein that plays a key role in cell proliferation and is likely to promote cancer development. The work may lead to the development of new diagnostic tools ...
Scientists crack mystery of protein's dual function
Dec 13, 2009 |
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Researchers at The Scripps Research Institute have solved a 10-year-old mystery of how a single protein from an ancient family of enzymes can have two completely distinct roles in the body. In addition to providing guidance ...
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