Transforming growth factor

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Transforming growth factor (sometimes referred to as Tumor growth factor, or TGF) is used to describe two classes of polypeptide growth factors, TGFα and TGFβ.

The name "Transforming Growth Factor" is somewhat arbitrary, since the two classes of TGFs are not structurally or genetically related to one another, and they act through different receptor mechanisms. Furthermore, they do not always induce cellular transformation, and are not the only growth factors that induce cellular transformation.

For more information about Transforming growth factor, read the full article at Wikipedia.
This text uses material from Wikipedia and is available under the GNU Free Documentation License.


News tagged with tumor growth


Possible ovarian cancer treatment target identified

Medicine & Health / Cancer

created Dec 08, 2009 | popularity not rated yet | comments 0

A multi-institutional study has identified a potential personalized treatment target for the most common form of ovarian cancer. In the December 8 issue of Cancer Cell, the research team describes finding that a gene called ...





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Decline of hormone therapy decreases breast cancer cases, analysis finds

Medicine & Health / Cancer

created 16 hours ago | popularity 2.5 / 5 (4) | comments 0

The declining use of hormone therapy among women has led to 6,000 fewer invasive breast cancer cases a year, according to an analysis by researchers at the University of Wisconsin-Madison. The research quantifies and advances ...


Penn Study Describes Novel Model of Skin Cancer

Study Describes Novel Model of Skin Cancer

Medicine & Health / Cancer

created 17 hours ago | popularity 5 / 5 (1) | comments 0

(PhysOrg.com) -- Scientists at the University of Pennsylvania School of Medicine have developed a new model of skin cancer based on the knowledge that a common cancer-related molecule called Src kinase is ...


Omega-3 fatty acids may reduce risk of colon cancer

Medicine & Health / Cancer

created Dec 08, 2009 | popularity 4 / 5 (1) | comments 0

Long-chain omega-3 fatty acids, primarily found in fish and seafood, may have a role in colorectal cancer prevention, according to results presented at the American Association for Cancer Research Frontiers in Cancer Prevention ...


Spices halt growth of breast stem cells, study finds

Medicine & Health / Cancer

created Dec 07, 2009 | popularity 5 / 5 (2) | comments 0

A new study finds that compounds derived from the spices turmeric and pepper could help prevent breast cancer by limiting the growth of stem cells, the small number of cells that fuel a tumor's growth.


New hope for diagnosis and treatment of intractable pediatric brain tumors

Medicine & Health / Cancer

created Dec 07, 2009 | popularity not rated yet | comments 0

Scientists have discovered oncogenes capable of driving growth of normal human brain stem cells in a highly malignant pediatric brain tumor. The research, published by Cell Press in the December issue of the journal Cancer Ce ...


New understanding of how to prevent destruction of a tumor suppressor

New understanding of how to prevent destruction of a tumor suppressor

Medicine & Health / Cancer

created Dec 07, 2009 | popularity not rated yet | comments 0

Researchers from the Indiana University School of Medicine and colleagues at the University of Texas Southwestern and Case Western University have determined how the protein Mdm2, which is elevated in late-stage ...


Tiny RNA has big impact on lung cancer tumors

Medicine & Health / Cancer

created Dec 07, 2009 | popularity 5 / 5 (3) | comments 0

Researchers from Yale University and Mirna Therapeutics, Inc., reversed the growth of lung tumors in mice using a naturally occurring tumor suppressor microRNA. The study reveals that a tiny bit of RNA may one day play a ...


'Live' imaging reveals breast cancer cells' transition to metastasis

Medicine & Health / Cancer

created Dec 06, 2009 | popularity not rated yet | comments 0

The spread, or metastasis, of individual breast cancer cells from the main tumor into the blood circulation to the lungs and other body tissues and organs is under the control of a growth factor abbreviated TGFb, according ...


Scientists use virus to kill cancer cells while leaving normal cells intact

Medicine & Health / Cancer

created Dec 03, 2009 | popularity 5 / 5 (7) | comments 3

(PhysOrg.com) -- A virus that in nature infects only rabbits could become a cancer-fighting tool for humans. Myxoma virus kills cancerous blood-precursor cells in human bone marrow while sparing normal blood stem cells, a ...


Random DNA mix-ups not so random in cancer development

Medicine & Health / Cancer

created Dec 03, 2009 | popularity not rated yet | comments 0

Researchers at the UC San Diego School of Medicine have pinpointed a mechanism that may help explain how chromosomal translocations - the supposedly random shuffling of large chunks of DNA that frequently lead to cancer - ...



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