News tagged with tumor suppression
Scientists demonstrate role of protein in distinguishing chromosome ends from DNA breaks
Sep 17, 2009 |
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The Stowers Institute's Baumann Lab has demonstrated how human cells protect chromosome ends from misguided repairs that can lead to cancer. The work, published in The EMBO Journal, a publication of the European Molecular Biolog ...
Waste disposal protein is mechanism behind cancer tumor suppression
Jun 11, 2009 |
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"Taking out the trash" takes on a whole new meaning, as investigators at The Cancer Institute of New Jersey (CINJ) and Rutgers, The State University of New Jersey, have discovered that a waste disposal protein is the key ...
Environmental exposures may damage DNA in as few as three days
May 17, 2009 |
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Exposure to particulate matter has been recognized as a contributing factor to lung cancer development for some time, but a new study indicates inhalation of certain particulates can actually cause some genes to become reprogrammed, ...
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Nanoparticle Developed To Boost Anti-Cancer Immunotherapy
Nanotechnology / Bio & Medicine
Feb 23, 2010 |
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(PhysOrg.com) -- One of the hallmarks of cancer is that tumors are able to suppress the immune system, preventing the body's own defense system from eliminating the disease, particularly as tumors spread through the body. ...
Researchers discover novel way to develop tumor vaccines
Mar 02, 2008 |
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Researchers at the University of Southern California (USC) have uncovered a new way to develop more effective tumor vaccines by turning off the suppression function of regulatory T cells. The results of the study, titled ...
Oncogene inhibits tumor suppressor to promote cancer: Study links B-RAF and LKB1
Jan 29, 2009 |
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Scientists have uncovered an interesting connection between two important protein kinase signaling pathways that are associated with cancer. The research, published by Cell Press in the January 30th issue of the journal Molecular Ce ...
Study finds way to protect healthy cells from radiation damage
Oct 21, 2009 |
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Researchers at the University of Pittsburgh School of Medicine and the National Cancer Institute (NCI), part of the National Institutes of Health, may be hot on the heels of a Holy Grail of cancer therapy: They have found ...
New findings may improve treatment of inherited breast cancer
Oct 09, 2008 |
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Scientists have identified some of the elusive downstream molecules that play a critical role in the development and progression of familial breast cancer. The research, published by Cell Press in the October 10th issue of ...
Cancer stem cells suppress immune response against brain tumor
Jan 15, 2010 |
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Cancer-initiating cells that launch glioblastoma multiforme, the most lethal type of brain tumor, also suppress an immune system attack on the disease, scientists from The University of Texas M. D. Anderson ...
Prostate Tumors Can Change the Function of Immune Cells in Mice
Oct 07, 2009 |
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(PhysOrg.com) -- Researchers have discovered that prostate tumors in mice can cause immune cells known as CD8+ T cells to change their function from cells that have antitumor activity to cells that suppress immune responses. ...
New understanding of how to prevent destruction of a tumor suppressor
Dec 07, 2009 |
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Researchers from the Indiana University School of Medicine and colleagues at the University of Texas Southwestern and Case Western University have determined how the protein Mdm2, which is elevated in late-stage ...
RNA interference toward MMP-2 may be an effective therapeutic strategy for cancer
Mar 09, 2009 |
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The invasion or metastasis of pancreatic cancer has been known to be a complex process involving many molecular mechanisms, of which proteolytic degradation of extracellular matrix (ECM) exerted by matrix metalloproteinases ...
How advanced prostate cancer becomes resistant to androgen-deprivation therapy
Jun 01, 2008 |
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For the past 70 years the treatment of choice for advanced, metastatic prostate cancer has been androgen-deprivation therapy. That is, the suppression of circulating testosterone – the hormone that fuels prostate-cancer growth ...
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