The tumor suppressor protein p53 has been dubbed the "guardian of the genome" because it protects the DNA from stress or long-term damage by regulating the expression of numerous genes involved DNA repair, cell division and ...
Molecular & Computational biology
Jun 30, 2023
0
50
There is a tightly regulated balance between cell growth and death in healthy tissue. The loss of this balance is essentially what initiates cancer.
Cell & Microbiology
Oct 19, 2022
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2
A trio of researchers with ICAEV, Universidad Austral de Chile, and the University of Liverpool, respectively, have found suppressor genes linked to longevity and less cancer in two species of whales. In their paper published ...
All things being equal, large, long-lived animals should have the highest risk of cancer.
Evolution
Feb 4, 2021
1
715
The gene p53 is extremely important in cell biology and, hence, the world of cell replacement therapy. Its role is to regulate the cell cycle and halt the formation of tumors, leading to its nickname the "tumor suppressor ...
Cell & Microbiology
Jun 1, 2020
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1
Researchers in Dana-Farber's cBio Center have now demonstrated a powerful 'experimental evolution' method to discover details of protein shape and function, and the method may find uses across a very broad spectrum of biomedical ...
Cell & Microbiology
Dec 11, 2019
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91
Gene editing has begun to be tested in clinical trials, using CRISPR-Cas9 and other technologies to directly edit DNA inside people's cells, and multiple trials are recruiting or in the planning stages. A new study led by ...
Biotechnology
Dec 11, 2017
0
104
Two studies publishing on 1st September in Open Access journal PLOS Biology identify overlapping groups of cells in the Drosophila larva that have unique properties. In one case, the cells are resistant to irradiation or ...
Cell & Microbiology
Sep 1, 2016
0
8
Regenerative medicine could one day allow physicians to correct congenital deformities, regrow damaged fingers, or even mend a broken heart. But to do it, they will have to reckon with the body's own anti-cancer security ...
Biotechnology
Nov 18, 2015
1
75
If DNA is the cookbook of life, then RNA is the scratch paper where the cell writes down its favorite recipes. These recipes could make the pigments of your skin, the vehicles that carry oxygen through your veins, or the ...
Biochemistry
May 27, 2015
0
1759
A tumor suppressor gene, or antioncogene, is a gene that protects a cell from one step on the path to cancer. When this gene is mutated to cause a loss or reduction in its function, the cell can progress to cancer, usually in combination with other genetic changes.
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