News tagged with tumor suppressor genes
New combination therapy could deliver powerful punch to breast cancer
Nov 16, 2009 |
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A powerful new breast cancer treatment could result from packaging one of the newer drugs that inhibits cancer's hallmark wild growth with another that blocks a primordial survival technique in which the cancer ...
Study identifies genetic cause of most common form of breast cancer
May 11, 2009 |
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The discovery of tumor-suppressor genes has been key to unlocking the molecular and cellular mechanisms leading to uncontrolled cell proliferation - the hallmark of cancer. Often, these genes will work in concert with others ...
New investigational treatment for bladder cancer
Mar 12, 2009 |
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A team of researchers, led by Columbia University Medical Center faculty, has identified a new investigational therapy for the treatment of bladder cancer. The discovery was made using a new research model, using mice, which ...
Prenatal molecular diagnosis for tuberous sclerosis complex
Mar 02, 2009 |
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Geneticists from Boston University School of Medicine (BUSM) have reported the world's first series of cases of prenatal diagnosis for women at risk of having a child with tuberous sclerosis complex (TSC). Earlier, the Center ...
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Cell biologists identify new tumor suppressor for lung cancer
Jan 05, 2009 |
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Cancer and cell biology experts at the University of Cincinnati (UC) have identified a new tumor suppressor that may help scientists develop more targeted drug therapies to combat lung cancer.
New discovery raises doubts about current bladder treatment
Mar 25, 2009 |
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Researchers at the University of Virginia Health System have found that one of the genes commonly thought to promote the growth and spread of some types of cancers is in fact beneficial in bladder cancer - a major discovery ...
Good fences make good neighbors
May 14, 2009 |
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Our genome is a patchwork of neighborhoods that couldn't be more different: Some areas are hustling and bustling with gene activity, while others are sparsely populated and in perpetual lock-down. Breaking ...
Novel marker of colon cancer
Oct 23, 2008 |
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Colon cancer ranks second of all gastrointestinal malignant tumors, it is one of the leading causes of cancer-related deaths worldwide. Until now, several molecules have been reported to play an important role in gastroenterological ...
Oncoproteins double-team and destroy vital tumor-suppressor
Feb 14, 2008 |
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Two previously unconnected cancer-promoting proteins team up to ambush a critical tumor suppressor by evicting it from the cell's nucleus and then marking it for death by a protein-shredding mechanism, a team led by scientists ...
Gene packaging tells story of cancer development
Biology /
Dec 04, 2008 |
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To decipher how cancer develops, Johns Hopkins Kimmel Cancer Center investigators say researchers must take a closer look at the packaging.
Gene found to play a suppressor role in skin cancer development
Feb 06, 2008 |
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Researchers at the Burnham Institute for Medical Research (Burnham Institute) have provided genetic evidence that Activating Transcription Factor 2 (ATF2) plays a suppressor role in skin cancer development. ATF2 is a protein ...
Fat droplet nanoparticle delivers tumor suppressor gene to tumor and metastatic cells
Nanotechnology / Bio & Medicine
Apr 20, 2009 |
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Dr. Esther Chang describes the most recent developments in human trials of the first systemic, non-viral, tumor-targeted, nanoparticle method designed to restore normal gene function to tumor cells while completely bypassing ...
Algorithm developed to detect cancer genes
May 09, 2006 |
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New York scientists say they have developed an algorithm that enhances the ability to detect cancer genes.
Does sugar feed cancer?
Aug 17, 2009 |
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Researchers at Huntsman Cancer Institute at the University of Utah have uncovered new information on the notion that sugar "feeds" tumors. The findings may also have implications for other diseases such as diabetes. The research ...
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