News tagged with tumor suppressor protein


Novel 'On-Off Switch' Mechanism Stops Cancer in Its Tracks

Novel 'On-Off Switch' Mechanism Stops Cancer in Its Tracks

Medicine & Health / Cancer

created Sep 11, 2009 | popularity 4.9 / 5 (32) | comments 6

(PhysOrg.com) -- A tiny bit of genetic material with no previously known function may hold the key to stopping the spread of cancer, researchers at Yale School of Medicine and Sichuan University in Chengdu, ...


Research shows cell's inactive state is critical for effectiveness of cancer treatment

Biology /

created Jan 09, 2009 | popularity 5 / 5 (1) | comments 0

A new study sheds light on a little understood biological process called quiescence, which enables blood-forming stem cells to exist in a dormant or inactive state in which they are not growing or dividing. According to the ...





Search results for tumor suppressor protein


New suppressor of common liver cancer

Medicine & Health / Cancer

created Dec 15, 2009 | popularity not rated yet | comments 0

Tumor suppressor genes make proteins that help control cell growth. Mutations in these genes that generate nonfunctional proteins can contribute to tumor development and progression. One of the most well-known tumor suppressor ...


New understanding of how to prevent destruction of a tumor suppressor

New understanding of how to prevent destruction of a tumor suppressor

Medicine & Health / Cancer

created Dec 07, 2009 | popularity not rated yet | comments 0

Researchers from the Indiana University School of Medicine and colleagues at the University of Texas Southwestern and Case Western University have determined how the protein Mdm2, which is elevated in late-stage ...


Tumor suppressor gene in flies may provide insights for human brain tumors

Medicine & Health / Cancer

created Jun 22, 2009 | popularity 5 / 5 (1) | comments 0

In the fruit fly's developing brain, stem cells called neuroblasts normally divide to create one self-renewing neuroblast and one cell that has a different fate. But neuroblast growth can sometimes spin out of control and ...


Cell biologists identify new tumor suppressor for lung cancer

Medicine & Health / Cancer

created Jan 05, 2009 | popularity not rated yet | comments 0

Cancer and cell biology experts at the University of Cincinnati (UC) have identified a new tumor suppressor that may help scientists develop more targeted drug therapies to combat lung cancer.


Gene helps protect tumor suppressor in breast cancer

Medicine & Health / Cancer

created Apr 06, 2009 | popularity not rated yet | comments 0

Scientists at The University of Texas M. D. Anderson Cancer Center have discovered a gene that protects PTEN, a major tumor-suppressor that is reduced but rarely mutated in about half of all breast cancers.


A surprise 'spark' for pre-cancerous colon polyps

Medicine & Health / Cancer

created May 14, 2009 | popularity 4 / 5 (1) | comments 0

Researchers at Huntsman Cancer Institute (HCI) at the University of Utah studied the events leading to colon cancer and found that an unexpected protein serves as the "spark" that triggers formation of colon polyps, the precursors ...


Oncoproteins double-team and destroy vital tumor-suppressor

Medicine & Health / Cancer

created Feb 14, 2008 | popularity not rated yet | comments 0

Two previously unconnected cancer-promoting proteins team up to ambush a critical tumor suppressor by evicting it from the cell's nucleus and then marking it for death by a protein-shredding mechanism, a team led by scientists ...


Promising biomarker and candidate tumor suppressor gene identified for colorectal cancer

Medicine & Health / Cancer

created Jun 18, 2009 | popularity not rated yet | comments 0

Researchers have identified a new candidate tumor suppressor gene in colorectal cancer and examined its use as a potential biomarker in stool samples, according to a new study published online June 17 in the Journal of th ...


Preventing prostate cancer the complex way

Preventing prostate cancer the complex way

Medicine & Health / Cancer

created Feb 03, 2009 | popularity 5 / 5 (1) | comments 0

(PhysOrg.com) -- Blocking a specific protein complex prevents the formation of tumors in mice genetically predisposed to develop prostate cancer, researchers at the Whitehead Institute for Biomedical Research ...


Bacterial peptide provides new insight into common tumor suppressor

Medicine & Health / Cancer

created Jul 07, 2008 | popularity 4 / 5 (1) | comments 0

Scientists have identified a new antitumor drug that might prove useful in developing treatments for a multiple human cancers. The research, published by Cell Press in the July 8 issue of the journal Cancer Cell, advances the un ...



List of search results for tumor suppressor protein