Tumor suppressor gene
hideA tumor suppressor gene, or antioncogene, is a gene that protects a cell from one step on the path to cancer. When this gene is mutated to cause a loss or reduction in its function, the cell can progress to cancer, usually in combination with other genetic changes.
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News tagged with tumor suppressor
Discovery in worms points to more targeted cancer treatment
Nov 10, 2009 |
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Researchers at Queen's University have found a link between two genes involved in cancer formation in humans, by examining the genes in worms. The groundbreaking discovery provides a foundation for how tumor-forming ...
Loss of tumor supressor gene essential to transforming benign nerve tumors into cancers
Oct 13, 2009 |
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Researchers at UCLA's Jonsson Comprehensive Cancer Center showed for the first time that the loss or decreased expression of the tumor suppressor gene PTEN plays a central role in the malignant transformation of benign nerve ...
Using RNAi-based technique, scientists find new tumor suppressor genes in lymphoma
Oct 13, 2009 |
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Researchers from Cold Spring Harbor Laboratory (CSHL) have uncovered a large, new cache of genes that act as built-in barriers against cancer. Known as tumor suppressors, the newly identified genes and the insight that they ...
KEAP1 Keeps major cancer-promoting protein at bay
Oct 09, 2009 |
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A tumor-suppressing protein snatches up an important cancer-promoting enzyme and tags it with molecules that condemn it to destruction, a research team led by scientists at The University of Texas M. D. Anderson ...
Novel 'On-Off Switch' Mechanism Stops Cancer in Its Tracks
Sep 11, 2009 |
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(PhysOrg.com) -- A tiny bit of genetic material with no previously known function may hold the key to stopping the spread of cancer, researchers at Yale School of Medicine and Sichuan University in Chengdu, ...
New type of adult stem cells found in the prostate may be involved in prostate cancer development
Sep 09, 2009 |
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A new type of stem cell discovered in the prostate of adult mice can be a source of prostate cancer, according to a new study by researchers at the Herbert Irving Comprehensive Cancer Center at Columbia University Medical ...
Researchers find that protein believed to protect against cancer has a Mr. Hyde side
Sep 03, 2009 |
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In a biological rendition of fiction's Strange Case of Dr. Jekyll and Mr. Hyde, researchers from the Mayo Clinic campus in Florida and Harvard Medical School have found that a protein thought to protect against cancer development ...
Researchers discover new targets for treatment of invasive breast cancer
Aug 19, 2009 |
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Research led by Suresh Alahari, PhD, Associate Professor of Biochemistry and Molecular Biology at LSU Health Sciences Center New Orleans, has shown for the first time that a tiny piece of RNA appears to play a major role ...
Does sugar feed cancer?
Aug 17, 2009 |
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Researchers at Huntsman Cancer Institute at the University of Utah have uncovered new information on the notion that sugar "feeds" tumors. The findings may also have implications for other diseases such as diabetes. The research ...
Gene vital to brain's stem cells implicated in deadly brain cancer
Aug 17, 2009 |
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Researchers from Columbia University Medical Center's Herbert Irving Comprehensive Cancer Center have identified a protein that activates brain stem cells to make new neurons - but that may be hijacked later in life to cause ...
Tumor suppressor pulls double shift as reprogramming watchdog
Aug 09, 2009 |
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A collaborative study by researchers at the Salk Institute for Biological Studies uncovered that the tumor suppressor p53, which made its name as "guardian of the genome", not only stops cells that could become ...
Scientists discover novel tumor suppressor
Aug 03, 2009 |
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La Jolla Institute for Allergy & Immunology researchers studying an enzyme believed to play a role in allergy onset, instead have discovered its previously unknown role as a tumor suppressor that may be important in myeloproliferative ...
New location found for regulation of RNA fate
Jul 30, 2009 |
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Thousands of scientists and hundreds of software programmers studying the process by which RNA inside cells normally degrades may soon broaden their focus significantly.
Mathematical modeling predicts response to Herceptin
Jul 28, 2009 |
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Cancer researchers are turning to mathematical models to help answer important clinical questions, and a new paper in Cancer Research, a journal of the American Association for Cancer Research, illustrates how the techni ...
Preventing Prostate Cancer to Bone Metastasis
Jul 13, 2009 |
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(PhysOrg.com) -- In new research on prostate cancer to bone metastasis, Dr. Phillip Trackman of Boston University Henry M. Goldman School of Dental Medicine explains that the lysyl oxidase pro-peptide (LOX-PP) inhibits prostate ...
