Tumor suppressor gene
hideA tumor suppressor gene, or antioncogene, is a gene that protects a cell from one step on the path to cancer. When this gene is mutated to cause a loss or reduction in its function, the cell can progress to cancer, usually in combination with other genetic changes.
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News tagged with tumor suppressor
New combination therapy could deliver powerful punch to breast cancer
Nov 16, 2009 |
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A powerful new breast cancer treatment could result from packaging one of the newer drugs that inhibits cancer's hallmark wild growth with another that blocks a primordial survival technique in which the cancer ...
Novel 'On-Off Switch' Mechanism Stops Cancer in Its Tracks
Sep 11, 2009 |
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(PhysOrg.com) -- A tiny bit of genetic material with no previously known function may hold the key to stopping the spread of cancer, researchers at Yale School of Medicine and Sichuan University in Chengdu, ...
Discovery in worms points to more targeted cancer treatment
Nov 10, 2009 |
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Researchers at Queen's University have found a link between two genes involved in cancer formation in humans, by examining the genes in worms. The groundbreaking discovery provides a foundation for how tumor-forming ...
Does sugar feed cancer?
Aug 17, 2009 |
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Researchers at Huntsman Cancer Institute at the University of Utah have uncovered new information on the notion that sugar "feeds" tumors. The findings may also have implications for other diseases such as diabetes. The research ...
Carbohydrate acts as tumor suppressor
Jul 06, 2009 |
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Scientists at Burnham Institute for Medical Research (Burnham) have discovered that specialized complex sugar molecules (glycans) that anchor cells into place act as tumor suppressors in breast and prostate cancers. These ...
New melanoma tumor suppressor gene uncovered
Mar 29, 2009 |
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National Institutes of Health (NIH) researchers have identified a gene that suppresses tumor growth in melanoma, the deadliest form of skin cancer. The finding is reported today in the journal Nature Genetics as part of a s ...
Using RNAi-based technique, scientists find new tumor suppressor genes in lymphoma
Oct 13, 2009 |
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Researchers from Cold Spring Harbor Laboratory (CSHL) have uncovered a large, new cache of genes that act as built-in barriers against cancer. Known as tumor suppressors, the newly identified genes and the insight that they ...
Loss of tumor supressor gene essential to transforming benign nerve tumors into cancers
Oct 13, 2009 |
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Researchers at UCLA's Jonsson Comprehensive Cancer Center showed for the first time that the loss or decreased expression of the tumor suppressor gene PTEN plays a central role in the malignant transformation of benign nerve ...
Tumor suppressor pulls double shift as reprogramming watchdog
Aug 09, 2009 |
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A collaborative study by researchers at the Salk Institute for Biological Studies uncovered that the tumor suppressor p53, which made its name as "guardian of the genome", not only stops cells that could become ...
Preventing Prostate Cancer to Bone Metastasis
Jul 13, 2009 |
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(PhysOrg.com) -- In new research on prostate cancer to bone metastasis, Dr. Phillip Trackman of Boston University Henry M. Goldman School of Dental Medicine explains that the lysyl oxidase pro-peptide (LOX-PP) inhibits prostate ...
New type of adult stem cells found in the prostate may be involved in prostate cancer development
Sep 09, 2009 |
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A new type of stem cell discovered in the prostate of adult mice can be a source of prostate cancer, according to a new study by researchers at the Herbert Irving Comprehensive Cancer Center at Columbia University Medical ...
Fat droplet nanoparticle delivers tumor suppressor gene to tumor and metastatic cells
Nanotechnology / Bio & Medicine
Apr 20, 2009 |
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Dr. Esther Chang describes the most recent developments in human trials of the first systemic, non-viral, tumor-targeted, nanoparticle method designed to restore normal gene function to tumor cells while completely bypassing ...
Potent metastasis inhibitor identified
Jun 22, 2009 |
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Researchers at Children's Hospital Boston have isolated a potent inhibitor of tumor metastasis made by tumor cells, one that could potentially be harnessed as a cancer treatment. Their findings were published in the online ...
Toward new drugs that turn genes on and off
Jun 04, 2009 |
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Scientists in Michigan and California are reporting an advance toward development of a new generation of drugs that treat disease by orchestrating how genes in the body produce proteins involved in arthritis, ...
New location found for regulation of RNA fate
Jul 30, 2009 |
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Thousands of scientists and hundreds of software programmers studying the process by which RNA inside cells normally degrades may soon broaden their focus significantly.
