Tumor suppressor gene
hideA tumor suppressor gene, or antioncogene, is a gene that protects a cell from one step on the path to cancer. When this gene is mutated to cause a loss or reduction in its function, the cell can progress to cancer, usually in combination with other genetic changes.
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News tagged with tumor suppressor
Tiny RNA has big impact on lung cancer tumors
Dec 07, 2009 |
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Researchers from Yale University and Mirna Therapeutics, Inc., reversed the growth of lung tumors in mice using a naturally occurring tumor suppressor microRNA. The study reveals that a tiny bit of RNA may one day play a ...
Human Mdm2: A new molecular link to late-stage metastatic breast cancer
Dec 02, 2009 |
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A large proportion of late-stage breast cancers that have spread to other parts of the body (metastatic breast cancers) are characterized by overexpression of the protein Mdm2.
New understanding of how to prevent destruction of a tumor suppressor
Dec 07, 2009 |
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Researchers from the Indiana University School of Medicine and colleagues at the University of Texas Southwestern and Case Western University have determined how the protein Mdm2, which is elevated in late-stage ...
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Researchers prove key cancer theory
Dec 07, 2009 |
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Mayo Clinic researchers have proven the longstanding theory that changes in the number of whole chromosomes -- called aneuploidy -- can cause cancer by eliminating tumor suppressor genes. Their findings, which appear in the ...
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