Tumor suppressor gene
hideA tumor suppressor gene, or antioncogene, is a gene that protects a cell from one step on the path to cancer. When this gene is mutated to cause a loss or reduction in its function, the cell can progress to cancer, usually in combination with other genetic changes.
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News tagged with tumor suppressor
Tiny RNA has big impact on lung cancer tumors
Dec 07, 2009 |
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Researchers from Yale University and Mirna Therapeutics, Inc., reversed the growth of lung tumors in mice using a naturally occurring tumor suppressor microRNA. The study reveals that a tiny bit of RNA may one day play a ...
Novel 'On-Off Switch' Mechanism Stops Cancer in Its Tracks
Sep 11, 2009 |
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(PhysOrg.com) -- A tiny bit of genetic material with no previously known function may hold the key to stopping the spread of cancer, researchers at Yale School of Medicine and Sichuan University in Chengdu, ...
Does sugar feed cancer?
Aug 17, 2009 |
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Researchers at Huntsman Cancer Institute at the University of Utah have uncovered new information on the notion that sugar "feeds" tumors. The findings may also have implications for other diseases such as diabetes. The research ...
Carbohydrate acts as tumor suppressor
Jul 06, 2009 |
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Scientists at Burnham Institute for Medical Research (Burnham) have discovered that specialized complex sugar molecules (glycans) that anchor cells into place act as tumor suppressors in breast and prostate cancers. These ...
New melanoma tumor suppressor gene uncovered
Mar 29, 2009 |
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National Institutes of Health (NIH) researchers have identified a gene that suppresses tumor growth in melanoma, the deadliest form of skin cancer. The finding is reported today in the journal Nature Genetics as part of a s ...
Loss of tumor supressor gene essential to transforming benign nerve tumors into cancers
Oct 13, 2009 |
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Researchers at UCLA's Jonsson Comprehensive Cancer Center showed for the first time that the loss or decreased expression of the tumor suppressor gene PTEN plays a central role in the malignant transformation of benign nerve ...
Using RNAi-based technique, scientists find new tumor suppressor genes in lymphoma
Oct 13, 2009 |
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Researchers from Cold Spring Harbor Laboratory (CSHL) have uncovered a large, new cache of genes that act as built-in barriers against cancer. Known as tumor suppressors, the newly identified genes and the insight that they ...
New type of adult stem cells found in the prostate may be involved in prostate cancer development
Sep 09, 2009 |
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A new type of stem cell discovered in the prostate of adult mice can be a source of prostate cancer, according to a new study by researchers at the Herbert Irving Comprehensive Cancer Center at Columbia University Medical ...
Tumor suppressor pulls double shift as reprogramming watchdog
Aug 09, 2009 |
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A collaborative study by researchers at the Salk Institute for Biological Studies uncovered that the tumor suppressor p53, which made its name as "guardian of the genome", not only stops cells that could become ...
New location found for regulation of RNA fate
Jul 30, 2009 |
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Thousands of scientists and hundreds of software programmers studying the process by which RNA inside cells normally degrades may soon broaden their focus significantly.
Preventing Prostate Cancer to Bone Metastasis
Jul 13, 2009 |
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(PhysOrg.com) -- In new research on prostate cancer to bone metastasis, Dr. Phillip Trackman of Boston University Henry M. Goldman School of Dental Medicine explains that the lysyl oxidase pro-peptide (LOX-PP) inhibits prostate ...
Potent metastasis inhibitor identified
Jun 22, 2009 |
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Researchers at Children's Hospital Boston have isolated a potent inhibitor of tumor metastasis made by tumor cells, one that could potentially be harnessed as a cancer treatment. Their findings were published in the online ...
Tumor suppressor gene in flies may provide insights for human brain tumors
Jun 22, 2009 |
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In the fruit fly's developing brain, stem cells called neuroblasts normally divide to create one self-renewing neuroblast and one cell that has a different fate. But neuroblast growth can sometimes spin out of control and ...
Toward new drugs that turn genes on and off
Jun 04, 2009 |
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Scientists in Michigan and California are reporting an advance toward development of a new generation of drugs that treat disease by orchestrating how genes in the body produce proteins involved in arthritis, ...
Good fences make good neighbors
May 14, 2009 |
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Our genome is a patchwork of neighborhoods that couldn't be more different: Some areas are hustling and bustling with gene activity, while others are sparsely populated and in perpetual lock-down. Breaking ...
