News tagged with tyrosine
A new mouse could help understand how some lung cancer cells evade drug treatment
Dec 09, 2009 |
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Lung cancer is the leading cause of cancer mortality worldwide and lung adenocarcinoma is the most common type. Many cases of lung adenocarcinoma are attributed to a mutation in a gene for the epidermal growth factor receptor ...
Second-line CML drugs evoke faster response than front-line therapy
Dec 07, 2009 |
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Two medications approved as treatment for drug-resistant chronic myeloid leukemia continue to provide patients with quicker, better responses as a first treatment than the existing front-line drug, researchers at The University ...
Drug shows promise for T315I-mutated chronic myeloid leukemia
Dec 07, 2009 |
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Results from a phase II clinical trial indicate a novel drug may provide a treatment option for chronic myeloid leukemia (CML) patients who do not respond to current therapies, researchers from The University of Texas M. ...
Cancers' sweet tooth may be weakness
Nov 18, 2009 |
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The pedal-to-the-metal signals driving the growth of several types of cancer cells lead to a common switch governing the use of glucose, researchers at Winship Cancer Institute of Emory University have discovered.
Inventive combination of research approaches identifies new target for treating leukemia
Oct 05, 2009 |
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New research integrates sophisticated interdisciplinary approaches to solve a molecular mystery that may lead to alternative therapeutic strategies for acute myeloid leukemia (AML). The study, published by Cell Press in the ...
Masitinib -- targeted therapy for cancers, inflammatory diseases and neurological indications
Sep 30, 2009 |
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In new research published in the open-access, peer-reviewed scientific journal PLoS ONE, Dr Patrice Dubreuil and colleagues characterise the pharmacological profile of masitinib (AB1010), a novel tyrosine kinase inhibitor (TKI) ...
Lapatinib shows minimal effect against liver cancer
Sep 08, 2009 |
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Use of the molecularly targeted agent lapatinib to delay tumor growth and improve the survival of patients with inoperable hepatocellular carcinoma, or liver cancer, only benefited certain subgroups of patients. While results ...
Study reveals new genetic culprit in deadly skin cancer
Aug 31, 2009 |
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Drawing on the power of DNA sequencing, National Institutes of Health researchers have identified a new group of genetic mutations involved in the deadliest form of skin cancer, melanoma. This discovery is particularly encouraging ...
Improvement of liver stem cell engraftment by protein delivery
Aug 24, 2009 |
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Researchers at INSERM (France) have engineered a chimeric protein that increases cell survival, migration and proliferation to improve stem cell engraftment. The results, which appear in the September 2009 issue of Experimental Bi ...
Single host gene may hold key to treating both ebola and anthrax infections
Aug 20, 2009 |
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Research published by Army scientists indicates that a minor reduction in levels of one particular gene, known as CD45, can provide protection against two divergent microbes: the virus that causes Ebola hemorrhagic fever ...
Researchers uncover genetic link to age-related cataracts
Jul 31, 2009 |
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(PhysOrg.com) -- Bing-Cheng Wang, Ph.D., Case Western Reserve University School of Medicine professor of pharmacology and senior staff scientist at MetroHealth Medical Center, and Sudha K. Iyengar, Ph.D. professor of genetic ...
Biomarkers predict brain tumor's response to therapy
Jun 23, 2009 |
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A report in Cancer Research, a journal of the American Association for Cancer Research, highlights a new biomarker that may be useful in identifying patients with recurrent glioblastoma, or brain tumors, who would respon ...
FDA approves cancer treatment for dogs
Jun 03, 2009 |
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(AP) -- The Food and Drug Administration has approved the first drug made specifically to treat cancer in dogs.
'Smart bomb' drug delivery may increase effectiveness
Apr 21, 2009 |
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Researchers may have found a way to combine imaging with chemotherapy in a single agent for the treatment of prostate cancer, according to data presented at the American Association for Cancer Research 100th Annual Meeting ...
Can you hear me now?
Biology /
Jul 07, 2008 |
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When it comes to cellular communication networks, a primitive single-celled microbe that answers to the name of Monosiga brevicollis has a leg up on animals composed of billions of cells. It commands a signaling ...
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