News tagged with ubiquitin ligase
New protein identified in bacterial arsenal
Mar 03, 2009 |
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(PhysOrg.com) -- Nearly a billion years ago, bacteria evolved an insidious means of infecting their hosts — a syringe-like mechanism able to inject cells with stealthy hijacker molecules. These molecules, ...
Search results for ubiquitin ligase
Scientists show how ubiquitin chains are added to cell-cycle proteins
Dec 02, 2009 |
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Researchers from the California Institute of Technology (Caltech) have been able to view in detail, and for the first time, the previously mysterious process by which long chains of a protein called ubiquitin ...
KEAP1 Keeps major cancer-promoting protein at bay
Oct 09, 2009 |
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A tumor-suppressing protein snatches up an important cancer-promoting enzyme and tags it with molecules that condemn it to destruction, a research team led by scientists at The University of Texas M. D. Anderson ...
Chemical from Soil Bacteria Shows Potential Neuron Toxicity; Has Possible Parkinson's Implications
Medicine & Health / Neuroscience
Oct 06, 2009 |
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(PhysOrg.com) -- A chemical produced by common soil bacteria may kill neurons that produce dopamine, according to an article authored by University of Alabama researchers publishing Oct. 6. Dopamine neuron demise leads to ...
When proteins change partners
Sep 11, 2009 |
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Dieter Wolf, M.D., and colleagues at Burnham Institute for Medical Research (Burnham) have illuminated how competition between proteins enhances combinatorial diversity during ubiquitination (the process that marks proteins ...
Study reveals how a common virus eludes the immune system
Aug 31, 2009 |
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Viruses have numerous tricks for dodging the immune system. In the September 7, 2009 issue of the Journal of Cell Biology, Stagg et al. reveal a key detail in one of these stratagems, identifying a protein that enables cyto-m ...
Researchers identify new, cancer-causing role for protein
Aug 27, 2009 |
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The mainstay immune system protein TRAF6 plays an unexpected, key role activating a cell signaling molecule that in mutant form is associated with cancer growth, researchers at The University of Texas M. D. ...
Protein plays unexpected role protecting chromosome tips
Aug 13, 2009 |
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A protein specialist that opens the genomic door for DNA repair and gene expression also turns out to be a multi-tasking workhorse that protects the tips of chromosomes and dabbles in a protein-destruction ...
Unraveling how cells respond to low oxygen
Aug 05, 2009 |
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Gary Chiang, Ph.D., and colleagues at Burnham Institute for Medical Research (Burnham) have elucidated how the stability of the REDD1 protein is regulated. The REDD1 protein is a critical inhibitor of the mTOR signaling pathway, ...
Researchers pinpoint a new enemy for tumor-suppressor p53
Jun 26, 2009 |
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Researchers at The University of Texas M. D. Anderson Cancer Center have identified a protein that marks the tumor suppressor p53 for destruction, providing a potential new avenue for restoring p53 in cancer ...
Climbing the ladder to longevity: Critical enzyme pair identified
Jun 24, 2009 |
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Experiment after experiment confirms that a diet on the brink of starvation expands lifespan in mice and many other species. But the molecular mechanism that links nutrition and survival is still poorly understood. ...
List of search results for ubiquitin ligase
