News tagged with ubiquitin
A paradigm shift in immune response regulation
Mar 19, 2009 |
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Over the past decade various pieces of the puzzle how signal transmission controls immunity have been coming together. Now, in Cell an international team reports a paradigm shift in the regulation of immune response. Their ...
New protein identified in bacterial arsenal
Mar 03, 2009 |
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(PhysOrg.com) -- Nearly a billion years ago, bacteria evolved an insidious means of infecting their hosts — a syringe-like mechanism able to inject cells with stealthy hijacker molecules. These molecules, ...
Search results for ubiquitin
Scientists discover new way in which ubiquitin modifies transcriptional machinery
Dec 18, 2008 |
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During gene transcription – the process inside the nucleus of cells by which DNA, the genetic material, is copied into RNA molecules – a large, ever-changing multiprotein complex is enlisted to assist the DNA-copying enzyme ...
Quality control mechanism tags defective sperm cells inside the body
Biology /
Jan 23, 2008 |
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Defective sperm cells do not pass through the body unnoticed. A new University of Missouri study provides evidence that the body recognizes and tags defective sperm cells while they undergo maturation in the epididymis, a ...
When proteins change partners
Sep 11, 2009 |
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Dieter Wolf, M.D., and colleagues at Burnham Institute for Medical Research (Burnham) have illuminated how competition between proteins enhances combinatorial diversity during ubiquitination (the process that marks proteins ...
Enzyme for ubiquitin-dependent protein degradation linked to cellular senescence
Biology /
May 22, 2008 |
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A new study, published by Cell Press in the May 23rd issue of the journal Molecular Cell, identifies a pivotal role for the CUL7 E3 ubiquitin ligase in growth control. The research makes an exciting new connection betwee ...
Discovery of new protein could provide new understanding of male fertility
Aug 02, 2007 |
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Scientists have discovered a new enzyme involved in the degradation of proteins inside cells, a process that helps eliminate or recycle proteins that are no longer needed. The unexpected discovery, made by Marcus Groettrup, ...
Muscle atrophy through thick but not thin
Jun 08, 2009 |
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During desperate times, such as fasting, or muscle wasting that afflicts cancer or AIDS patients, the body cannibalizes itself, atrophying and breaking down skeletal muscle proteins to liberate amino acids. In a new study ...
Researchers identify novel mechanism for regulation of gene expression
Biology /
Sep 26, 2008 |
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The Stowers Institute's Conaway Lab has demonstrated that an enzyme called Uch37 is kept in check when it is part of a human chromatin remodeling complex, INO80. The results were published in today's issue of Molecular Ce ...
Glue inside the cell
Biology /
Oct 19, 2007 |
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The acquired immune response is triggered after specific engagement of foreign peptides (antigens) by receptor molecules on white blood cell (lymphocytes). Cellular signaling pathways are responsible for the activation of ...
Study opens a new door to understanding cancer
Aug 09, 2007 |
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An in-depth understanding of the mechanisms that trigger cancer cell growth is vital to the development of more targeted treatments for the disease. An article published in the August 3 issue of Molecular Cell provides a key ...
Discovery in plants suggests entirely new approach to treating human cancers
Biology /
Apr 04, 2007 |
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For the first time, scientists from the University of Washington School of Medicine, Indiana University Bloomington and the University of Cambridge have determined how a plant hormone -- auxin -- interacts with its hormone ...
List of search results for ubiquitin
