Ulcerative colitis
hideUlcerative colitis (Colitis ulcerosa, UC) is a form of inflammatory bowel disease (IBD). Ulcerative colitis is a form of colitis, a disease of the intestine, specifically the large intestine or colon, that includes characteristic ulcers, or open sores, in the colon. The main symptom of active disease is usually constant diarrhea mixed with blood, of gradual onset. Ulcerative colitis is, however, believed to have a systemic etiology that leads to many symptoms outside the intestine. Because of the name, IBD is often confused with irritable bowel syndrome ("IBS"), a troublesome, but much less serious, condition. Ulcerative colitis has similarities to Crohn's disease, another form of IBD. Ulcerative colitis is an intermittent disease, with periods of exacerbated symptoms, and periods that are relatively symptom-free. Although the symptoms of ulcerative colitis can sometimes diminish on their own, the disease usually requires treatment to go into remission.
Ulcerative colitis occurs in 35–100 people for every 100,000 in the United States, or less than 0.1% of the population. The disease tends to be more common in northern areas. Although ulcerative colitis has no known cause, there is a presumed genetic component to susceptibility. The disease may be triggered in a susceptible person by environmental factors. Although dietary modification may reduce the discomfort of a person with the disease, ulcerative colitis is not thought to be caused by dietary factors. Although ulcerative colitis is treated as though it were an autoimmune disease, there is no consensus that it is such. Treatment is with anti-inflammatory drugs, immunosuppression, and biological therapy targeting specific components of the immune response. Colectomy (partial or total removal of the large bowel through surgery) is occasionally necessary, and is considered to be a cure for the disease.
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News tagged with ulcerative colitis
Cause of common chronic diarrhea revealed in new research
Nov 02, 2009 |
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(PhysOrg.com) -- A common type of chronic diarrhoea may be caused by a hormone deficiency, according to new research published in the November issue of Clinical Gastroenterology and Hepatology. The author ...
Study reveals possible link between IBD therapy and skin cancer
Oct 26, 2009 |
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Findings from a new retrospective cohort study presented at the American College of Gastroenterology's 74th Annual Scientific meeting in San Diego indicate that patients with Inflammatory Bowel Disease (IBD), especially ...
Probiotic found to be effective treatment for colitis in mice
Oct 26, 2009 |
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The probiotic, Bacillus polyfermenticus, can help mice recover from colitis, a new study has found. Mice treated with B. polyfermenticus during the non-inflammatory period of the disease had reduced rectal bleeding, their tissues ...
Researchers find triggers in cells' transition from colitis to cancer
Oct 12, 2009 |
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(PhysOrg.com) -- University of Florida researchers have grown tumors in mice using cells from inflamed but noncancerous colon tissue taken from human patients, a finding that sheds new light on colon cancer ...
Oxidized form of a common vitamin may bring relief for ulcerative colitis
Oct 01, 2009 |
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Here's another reason why you should take your vitamins. A new research report appearing in the October 2009 print issue of the Journal of Leukocyte Biology suggests that retinoic acid, the oxidized form of vitamin A, cou ...
Ulcerative colitis treatment reduces need for surgery by almost half
Oct 01, 2009 |
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A new study led by Mayo Clinic researchers has found that ulcerative colitis patients had a 41 percent reduction in colectomy after a year when treated with infliximab, according to a study published in the October 2009 issue ...
Curcumin May be Viable Supplement to Treat Inflammatory Bowel Disease
Jul 27, 2009 |
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(PhysOrg.com) -- Turmeric - the key ingredient in curry - has been used in India for thousands of years to help treat colds, inflammation, arthritis and even cancer.
Electronic pill shows its smarts by measuring pH levels in digestive tract
Jun 03, 2009 |
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An electronic diagnostic tool called the SmartPill is swallowed by patients in order to take measurements as it travels through the gastrointestinal tract. A new study by physician-scientists at NewYork-Presbyterian/Weill ...
Enzyme involved in inflammatory bowel disease discovered
Jun 02, 2009 |
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Researchers at Penn State College of Medicine, working with biochemists, geneticists and clinicians at the University of Bern, Switzerland and in the United Kingdom, have discovered an enzyme that has a key role in inflammatory ...
No longer afraid to be a bridesmaid or travel with the boss
May 13, 2009 |
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One of Laurie Keefer's patients was afraid to be a bridesmaid in a friend's wedding, others worried about traveling with the boss or even going to parties in peoples' homes.
Stem cell focus for IBD wound healing
Apr 28, 2009 |
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Scientists at The University of Nottingham are investigating whether stem cell markers could have a role to play in speeding up wound healing in patients suffering from inflammatory bowel disease (IBD).
Helping hand of hybrid surgery benefits colorectal patients
Apr 15, 2009 |
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Despite rapid strides in minimally invasive surgical techniques -- most notably, laparoscopy -- traditional open surgery remains the most common surgical option across the United States for people with diseases of the rectum ...


