News tagged with viral vectors

Using plants to silence insect genes in a high-throughput manner

Scientists at the Max Planck Institute for Chemical Ecology, Germany, are now using a procedure which brings forward ecological research on insects: They study gene functions in moth larvae by manipulating ...

Biology / Biotechnology

created Feb 02, 2012 | popularity 5 / 5 (2) | comments 1 | with audio podcast

Gene therapy research cures retinitis pigmentosa in dogs

Members of a University of Pennsylvania research team have shown that they can prevent, or even reverse, a blinding retinal disease, X-linked Retinitis Pigmentosa, or XLRP, in dogs.

Medicine & Health / Genetics

created Jan 23, 2012 | popularity 4.9 / 5 (11) | comments 0 | with audio podcast

Can nerve growth factor gene therapy prevent diabetic heart disease?

Diabetes is a major risk factor for cardiovascular disease and can reduce blood supply to the heart tissue and damage cardiac cells, resulting in heart failure. New research has investigated if nerve growth factor (NGF) gene ...

Medicine & Health / Diseases

created Dec 20, 2011 | popularity 5 / 5 (2) | comments 1 | with audio podcast

Ohio State researchers design a viral vector to treat a genetic form of blindness

Researchers at Ohio State University Medical Center and Nationwide Children's Hospital have developed a viral vector designed to deliver a gene into the eyes of people born with an inherited, progressive form of blindness ...

Medicine & Health / Research

created Nov 02, 2011 | popularity not rated yet | comments 0

New complex offers potentially safer alternative for gene therapy delivery

Spontaneous ordering of DNA fragments in a special matrix holds the key to creating non-toxic gene therapy delivery vectors, according to a study recently published in the European Physical Journal E.

Biology / Biotechnology

created Sep 08, 2011 | popularity not rated yet | comments 0

Advances in delivery of therapeutic genes to treat brain tumors

Novel tools and methods for delivering therapeutic genes to cells in the central nervous system hold great promise for the development of new treatments to combat incurable neurologic diseases. Five of the ...

Medicine & Health / Genetics

created Jun 27, 2011 | popularity 5 / 5 (1) | comments 0

Plant pathologist finding Kansas wheat fields a molecular battleground this season

With harvest in full swing, many farmers have found that the brutal combination of high winds, scorching temperatures and minimal rainfall has left most wheat yields looking less like the good or the bad and more like the ...

Biology / Biotechnology

created Jun 22, 2011 | popularity not rated yet | comments 0

NIH grant for the move toward clinical trials targeting the lysosomal storage disease MPSIIIB

Investigators at Nationwide Children's have received a grant from the National Institutes of Health (NIH) to help move a therapy for MPS IIIB that has been shown effective in mice toward clinical trials in humans.

Medicine & Health / Research

created May 25, 2011 | popularity not rated yet | comments 0

Gene therapy success depends on ability to advance viral delivery vectors to commercialization

Many gene therapy strategies designed to deliver a normal copy of a gene to cells carrying a disease-causing genetic mutation rely on a modified virus to transfer the gene product into affected tissues. One ...

Medicine & Health / Genetics

created May 18, 2011 | popularity not rated yet | comments 0

First vaccine for viral hepatitis C could become a reality

Berlin, Germany, Friday 01 April 2011: Early data from phase I trials of an HCV vaccine presented today at the International Liver CongressTM show encouraging results, with high immunogenicity and good safety profile.1,2

Medicine & Health / Diseases

created Apr 01, 2011 | popularity not rated yet | comments 0

Scientists design new delivery device for gene therapy

Scientists have designed a nanoparticle that appears to effectively deliver genetic material into cells with minimal toxic effects.

Medicine & Health / Genetics

created Jul 06, 2010 | popularity 4.9 / 5 (9) | comments 1 | with audio podcast

Gene therapy sets stage for new treatments for inherited blindness, researchers say

Veterinary vision scientists at the University of Pennsylvania have safely and successfully used a viral vector in targeting a class of photoreceptors of the retina called rods, a critical first step in developing ...

Medicine & Health / Genetics

created Apr 29, 2010 | popularity 5 / 5 (1) | comments 0

Study: Gene therapy reverses effects of lethal childhood muscle disorder in mice

Reversing a protein deficiency through gene therapy can correct motor function, restore nerve signals and improve survival in mice that serve as a model for the lethal childhood disorder spinal muscular atrophy, new research ...

Biology / Biotechnology

created Feb 28, 2010 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Anti-aging gene linked to high blood pressure

Researchers at the University of Oklahoma Health Sciences Center have shown the first link between a newly discovered anti-aging gene and high blood pressure. The results, which appear this month in the journal ...

Medicine & Health / Genetics

created Aug 19, 2009 | popularity 5 / 5 (12) | comments 3

Vaporized viral vector shows promise in anti-cancer gene therapy

A new lung cancer therapy employing a vaporized viral vector to deliver a cancer-inhibiting molecule directly to lung tissue shows early promise in mouse trials, according to researchers at the Ministry of Education, Science ...

Medicine & Health / Cancer

created Jun 08, 2009 | popularity 5 / 5 (2) | comments 0