News tagged with wnt pathway
Researchers discover possible new target for sarcoma treatment and prevention
Researchers from Mount Sinai School of Medicine have discovered a protein signaling pathway that becomes hyperactivated in human sarcoma cells, suggesting that medications to inhibit this pathway may be effective in the treatment ...
May 23, 2011 |
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Ancient gene gives planarians a heads-up in regeneration
A seldom-studied gene known as notum plays a key role in the planarian's regeneration decision-making process, according to Whitehead Institute scientists. Protein from this gene determines whether a head or tail will regrow ...
May 12, 2011 |
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Small molecules inhibit growth of human tumor cells
Researchers from the Cancer Institute at NYU Langone Medical Center have identified three novel small molecules that interrupt a crucial cellular communication pathway that regulates many aspects of development ...
Apr 13, 2011 |
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Gut microbes promote cell turnover by a well-known pathway
Microbes matter -- perhaps more than anyone realizes -- in basic biological development and, maybe, they could be a target for reducing cancer risks, according to University of Oregon researchers.
Oct 07, 2010 |
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Exosomal release of beta-catenin may explain why CD82 and CD9 suppress tumor metastasis
Researchers reveal a new way in which cells restrain beta-catenin and potentially suppress tumor metastasis: the protein can be ejected from cells in small vesicles called exosomes. The study appears online ...
Sep 13, 2010 |
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Tumor suppressor APC could stop cancer through its effect on actin cytoskeleton
The APC protein serves as the colon's guardian, keeping tumors at bay. Now researchers reveal a new function for the protein: helping to renovate the cytoskeleton by triggering actin assembly. The result suggests ...
Jun 21, 2010 |
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Tapeworm Drug May Hold Promise For Colon Cancer, Future Research
(PhysOrg.com) -- Duke University Medical Center researchers have discovered an already-FDA-approved compound that can effectively “silence” a cell receptor shown to interfere with chemotherapy.
Nov 04, 2009 |
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How to make a lung: Cell-regeneration molecules essential signals for early lung development
A tissue-repair-and-regeneration pathway in the human body, including wound healing, is essential for the early lung to develop properly. Genetically engineered mice fail to develop lungs when two molecules ...
Aug 17, 2009 |
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Targeting breast cancer stem cells in mice
Cancer develops when cells known as cancer stem cells begin to divide in an uncontrolled manner. Researchers from the University of Michigan Comprehensive Cancer Center have identified roles for the gene PTEN, ...
Jun 02, 2009 |
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