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Biochemistry 4 hours ago

Novel chemical tool for understanding membrane remodeling in the cell

In a study published in Proceedings of the National Academy of Sciences, Umeå researchers describe a natural product-like molecule, Tantalosin, that inhibits interaction between two proteins in complexes that reshape membranes ...

Biochemistry 22 hours ago

Centipedes used in traditional Chinese medicine offer leads for kidney treatment

A venomous, 8-inch centipede may be the stuff of nightmares, but it could save the life of those affected by kidney disease. Researchers report in the Journal of Natural Products that the many-legged critter—used in traditional ...

Bio & Medicine 23 hours ago

Nano-drugs hitching a ride on bacteria could help treat pancreatic cancer

Many pancreatic tumors are like malignant fortresses, surrounded by a dense matrix of collagen and other tissue that shields them from immune cells and immunotherapies that have been effective in treating other cancers. Employing ...

Environment 23 hours ago

Scientists advance research of harmful PFAS chemicals and their impacts

A bemused fishmonger at a seafood market in Portsmouth, N.H., weighed and packaged a dozen filets of fish and three lobster tails for his unusually exacting customers, Dartmouth researchers Celia Chen, Guarini, a research ...

Bio & Medicine May 2, 2024

Developing a tech platform for fast, robust series production of nanoparticles

Nucleic acid-based medications such as mRNA vaccines offer tremendous potential for medicine and are opening up new therapeutic approaches. These active ingredients must be enclosed inside nanoparticles to ensure that they ...

Analytical Chemistry May 2, 2024

Chemists use new approach in the synthesis of complex natural substances

They are found as fragrances in cosmetics or as flavorings in food, and form the basis of new medications: Terpenes are natural substances that occur in plants, insects and sea sponges. They are difficult to produce synthetically. ...

Cell & Microbiology May 2, 2024

Antimicrobial peptide from cows shows potential for treating hypervirulent bacteria

University of Central Florida College of Medicine researcher Renee Fleeman is on a mission to kill drug-resistant bacteria, and her latest study has identified a therapy that can penetrate the slime that such infections use ...

Cell & Microbiology May 2, 2024

Understanding cellular transcription responses to oxygen deprivation

A multiprotein complex is essential for regulating cellular responses to oxygen deprivation, a key feature of cancer, according to a Northwestern Medicine study published in the Proceedings of the National Academy of Sciences.

Cell & Microbiology May 1, 2024

Study: Airway hillocks challenge our understanding of lung biology

Airway hillocks are mysterious, flat-topped structures that were only recently identified within regular lung tissue, and their role in airway biology and pathology has previously been unknown.

Environment May 1, 2024

Tire toxicity faces fresh scrutiny after salmon die-offs

For decades, concerns about automobile pollution have focused on what comes out of the tailpipe. Now, researchers and regulators say, we need to pay more attention to toxic emissions from tires as vehicles roll down the road.

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