Process to customize molecules does double duty

Inspired by your liver and activated by light, a chemical process developed in labs at Rice University and in China shows promise for drug design and the development of unique materials.

Novel role of progestin signaling in fish spermatogenesis

Cytochrome P450, family 17, subfamily A, polypeptide 1 (cyp17a1) is a critical enzyme involved in gonadal steroidogenesis, including androgen and estrogen production. Among sex steroids, androgen signaling disruption is known ...

Plant scientists find recipe for anti-cancer compound in herbs

Thyme and oregano possess an anti-cancer compound that suppresses tumor development, but adding more to your tomato sauce isn't enough to gain significant benefit. The key to unlocking the power of these plants is in amplifying ...

Herbicide resistance no longer a black box for scientists

When agricultural weeds evolve resistance to herbicides, they do it in one of two ways. In target-site resistance, a tiny mutation in the plant's genetic code means the chemical no longer fits in the protein it's designed ...

Steroid binding to metabolic enzyme

The human cytochrome P450 enzymes are responsible for metabolizing a variety of substances—from lipids (fats) and steroid hormones to drugs and toxic chemicals.

Surprising enzymes found in giant ocean viruses

A new study led by researchers at Woods Hole Oceanographic Institution (WHOI) and Swansea University Medical School furthers our knowledge of viruses—in the sea and on land— and their potential to cause life-threatening ...

Heat-resistant enzymes could produce more cost-effective drugs

A new study published in Proceedings of the National Academy of Sciences could change the way scientists look at one of the most essential enzymes in medicine in hopes of designing better and more cost-effective drugs in ...

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