News tagged with repair
Newly discovered heart stem cells make muscle and bone
Researchers have identified a new and relatively abundant pool of stem cells in the heart. The findings in the December issue of Cell Stem Cell, a Cell Press publication, show that these heart cells have the capacity for lo ...
Dec 01, 2011 |
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Molecular corkscrew
Scientists from the universities of Zurich and Duisburg-Essen have discovered a specific function of the protein p97/VCP. They demonstrate that the protein repairs DNA breaks like a corkscrew, a repair mechanism that could ...
Nov 08, 2011 |
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First evidence of new 'druggable' DNA repair target to destroy cancer cells
(Medical Xpress) -- Blocking a key DNA damage repair enzyme, called APE1, could provide a new way to kill cancer cells containing faulty BRCA genes, according to research presented at the National Cancer Research Institute ...
Nov 07, 2011 |
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Why some kidney disease patients can't repair blood vessels
In some kidney diseases, patients have high blood levels of a protein that blocks blood vessel repair, according to a study appearing in an upcoming issue of the Journal of the American Society Nephrology (JASN). Inhibiting th ...
Oct 27, 2011 |
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Findings suggest how cancer cells can become resistant to DNA damage-inducing treatments
An international team of scientists led by UC Davis researchers has discovered that DNA repair in cancer cells is not a one-way street as previously believed. Their findings show instead that recombination, an important DNA ...
Oct 23, 2011 |
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Ovarian cancer patients survive longer with BRCA2 mutated in tumors
Women with high-grade ovarian cancer live longer and respond better to platinum-based chemotherapy when their tumors have BRCA2 genetic mutations, researchers at The University of Texas MD Anderson Cancer Center and the Institute ...
Oct 11, 2011 |
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Stem cells, signaling pathways identified in lung repair
(Medical Xpress) -- Researchers at National Jewish Health have identified cells and signaling molecules that trigger the repair of injured lungs. Stijn De Langhe, PhD, and his colleagues report October 10, 2011, online in ...
Oct 11, 2011 |
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Biochemists identify how tissue cells detect and perfect
Scientists have discovered how cells detect tissue damage and modify their repair properties accordingly. The findings, published today [6 October] in the journal Developmental Cell, could open up new opportunities for im ...
Oct 06, 2011 |
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Rebooting the system: Immune cells repair damaged lung tissues after flu infection
There's more than one way to mop up after a flu infection. Now, researchers from the Perelman School of Medicine at the University of Pennsylvania report in Nature Immunology that a previously unrecognized popula ...
Oct 03, 2011 |
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Biochemists identify new genetic code repair tool
Clemson University researchers recently reported finding a new class of DNA repair-makers.
Sep 27, 2011 |
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Bacteria shed light on new drug targets for inherited cancers
Cancer Research UK scientists have succeeded in purifying a protein found in bacteria that could reveal new drug targets for inherited breast and ovarian cancers - and other cancers linked to DNA repair faults. The study ...
Sep 06, 2011 |
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Controlling self-renewal of stem cells
(PhysOrg.com) -- Scientists from the Friedrich Miescher Institute for Biomedical Research (FMI) are the first to establish a direct link between a conserved stem cell factor and the cell cycle regulation in ...
Sep 02, 2011 |
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A question of gene silencing
When investigating cancer cells, researchers discovered numerous peculiarities: Particular RNA molecules are present in large numbers, particular genes are overactive. Do these characteristics have a relation to cancer? Do ...
Aug 24, 2011 |
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Olaparib shows promise in treating ovarian cancer, even without BRCA mutations
The PARP inhibitor, olaparib, that has shown promise in women with an inherited mutation in their BRCA1 or BRCA2 gene (accounting for about 5-10% of breast and ovarian cancer cases), has, for the first time, been shown to ...
Aug 21, 2011 |
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Researchers reveal a new mechanism of genomic instability
Researchers at NYU School of Medicine have discovered the cellular mechanisms that normally generate chromosomal breaks in bacteria such as E. coli. The study's findings are published in the August 18 issue of the journal ...
Aug 18, 2011 |
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