News tagged with signaling
New drug shows promise in the fight against malignant melanoma
Sep 29, 2009 |
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(PhysOrg.com) -- Gavin Robertson is not a man who uses the word ‘hate’ lightly, but he makes no secret of his desire to slay the dragon that is malignant melanoma.
Scientists get detailed glimpse of chemoreceptor architecture in bacterial cells
Sep 24, 2009 |
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Using state-of-the-art electron microscopy techniques, a team led by researchers from Caltech has for the first time visualized and described the precise arrangement of chemoreceptors—the receptors that sense ...
Figuring out the heads or tails decision in regeneration
Sep 14, 2009 |
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Amputations trigger a molecular response that determines if a head or tail will be regrown in planaria, a flatworm commonly studied for its regenerative capabilities. Until now, no molecular connection between wounding and ...
Plants on Steroids: Key Missing Link Discovered
Sep 08, 2009 |
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(PhysOrg.com) -- Researchers at the Carnegie Institution's Department of Plant Biology have discovered a key missing link in the so-called signaling pathway for plant steroid hormones (brassinosteroids). Many important signaling ...
Lapatinib shows minimal effect against liver cancer
Sep 08, 2009 |
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Use of the molecularly targeted agent lapatinib to delay tumor growth and improve the survival of patients with inoperable hepatocellular carcinoma, or liver cancer, only benefited certain subgroups of patients. While results ...
Research shows why low vitamin D raises heart disease risks in diabetics
Aug 22, 2009 |
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Low levels of vitamin D are known to nearly double the risk of cardiovascular disease in patients with diabetes, and researchers at Washington University School of Medicine in St. Louis now think they know ...
Researchers identify potential target for metastatic cancer
Aug 10, 2009 |
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The deadliest part of the cancer process, metastasis, appears to rely on help from macrophages, potent immune system cells that usually defend vigorously against disease, researchers at Albert Einstein College ...
What makes stem cells tick?
Aug 06, 2009 |
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Investigators at the Burnham Institute for Medical Research (Burnham) and The Scripps Research Institute (TSRI) have made the first comparative, large-scale phosphoproteomic analysis of human embryonic stem cells (hESCs) ...
Cannibalistic cells may help prevent infections
Aug 03, 2009 |
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Infectious-disease specialists at UT Southwestern Medical Center have demonstrated that a cannibalistic process in cells plays a key role in limiting Salmonella infection.
Researchers discover new molecular pathway for targeting cancer, disease
Jul 20, 2009 |
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(PhysOrg.com) -- A UCLA study has identified a way to turn off a key signaling pathway involved in physiological processes that can also stimulate the development of cancer and other diseases. The findings may lead to new ...
Ready for relapse: Molecule helps breast cancer cells to survive in the bone marrow
Jul 06, 2009 |
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Patients who survive an initial diagnosis of breast cancer often succumb to the disease years later when the cancer shows up in a different part of the body. Now, scientists have identified key signals that support the long ...
Toxic chemicals affect steroid hormones differently in humans and invertebrates
Jun 29, 2009 |
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In a study with important consequences for studies on the effects of chemicals on steroid responses in humans, a team of French and American scientists, including Michael E. Baker, PhD, professor in UC San Diego's Department ...
A new take on growth factor signaling in tamoxifen resistance
Jun 24, 2009 |
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Differences in growth factor (GF) signaling may cause the poor prognosis in some breast cancer cases. A new study, published in the open access journal BMC Medical Genomics, suggests that some estrogen receptor-positive breast ...
Fate in fly sensory organ precursor cells could explain human immune disorder
Jun 21, 2009 |
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(June 21, 2009) - Notch signaling helps determine the fate of a number of different cell types in a variety of organisms, including humans. In an article that appears in the current issue of Nature Cell Biology, researchers at Bay ...
Signal failure indicates 'rapid' Air France catastrophe: official
Jun 01, 2009 |
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No signal has been heard from distress beacons on a missing Air France plane, indicating it suffered a "very rapid" catastrophe, a top French space agency official told AFP on Monday.
