The first study to compare the accumulation of mutations across many animal species has shed new light on decades-old questions about the role of these genetic changes in aging and cancer. Researchers from the Wellcome Sanger ...
Molecular & Computational biology
Apr 13, 2022
0
97
New work from the Kiel Evolution Center suggests that somatic gene variations play a larger role in evolutionary adaptation mechanisms than previously thought.
Evolution
Oct 1, 2021
4
523
Mount Sinai researchers have discovered how the enzyme DNA polymerase delta works to duplicate the genome that cells hand down from one generation to the next. In a study published in Nature Structural & Molecular Biology, ...
Molecular & Computational biology
Oct 3, 2019
0
397
The towering, hundred-year-old Sitka spruce trees growing in the heart of Vancouver Island's Carmanah Valley appear placid and unchanging.
Evolution
Jul 8, 2019
1
873
Scientists know that age and weight are risk factors in the development of cancer. That should mean that whales, which include some of the largest and longest-lived animals on Earth, have an outsized risk of developing cancer.
Molecular & Computational biology
May 9, 2019
1
266
Mutation rates are proposed to be a pragmatic balance struck between the harmful effects of mutations and the costs of suppressing them; this hypothesis predicts that longer-lived body parts and those that contribute to the ...
Biotechnology
Apr 9, 2019
0
33
Two new computational tools, MSMuTect and MSMutSig, could help reveal how often mutations in common DNA features called microsatellites appear in, and contribute to, cancer.
Biotechnology
Sep 12, 2017
0
58
Variations in the color of grapevine berries within the Pinot family result from naturally-occurring genetic mutations that selectively shut down the genes responsible for the synthesis of red pigments, called anthocyanins. ...
Biotechnology
Apr 2, 2015
0
12
New research in flies shows how cells in adult reproductive organs maintain their sexual identity. The study, publishing online on November 13 in the Cell Press journal Developmental Cell, also identified a mutation that ...
Cell & Microbiology
Nov 13, 2014
0
0
Researchers have developed new methods to trace the life history of individual cells back to their origins in the fertilised egg. By looking at the copy of the human genome present in healthy cells, they were able to build ...
Cell & Microbiology
Jun 29, 2014
1
0
