The tips of chromosomes have structures called telomeres comparable to the plastic cover at the end of shoelaces. They work as a protective cap that prevents genetic material from unfolding and corroding. When telomeres do ...
Cell & Microbiology
Feb 28, 2019
0
13
RUDN biochemists found a way to reduce the activity of telomerase (the enzyme of cell immortality) 10-fold. The discovery could lead to new antitumor drugs and give a better understanding of how the activity of the enzyme ...
Biochemistry
Feb 12, 2019
0
11
More than 30 years ago, when University of California, Berkeley researchers discovered telomerase—an enzyme that lengthens chromosome ends and prevents them from fraying enough to kill a cell—speculation ran wild about ...
Biochemistry
Apr 25, 2018
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1034
Scientists from Moscow State University (MSU) working with an international team of researchers have identified the structure of one of the key regions of telomerase—a so-called "cellular immortality" ribonucleoprotein. ...
Biochemistry
Mar 23, 2018
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19
Researchers at the Cancer Science Institute of Singapore (CSI Singapore) at the National University of Singapore (NUS) have identified a novel molecular pathway by which a tumour suppressor, TIP60, inhibits the growth of ...
Cell & Microbiology
Dec 7, 2017
0
4
As the rope of a chromosomes replicates, it frays at the ends. No problem: A chromosome's ends have extra twine so that fraying doesn't reach into the body of the rope where the important information resides. This extra twine ...
Cell & Microbiology
Aug 18, 2016
0
1548
An enzyme called telomerase plays a significant role in aging and most cancers, but until recently many aspects of the enzyme's structure could not be clearly seen.
Biochemistry
Oct 15, 2015
0
358
When a human cell divides, its daughter cells should each receive an identical copy of the mother cell's genome. Occasionally mistakes occur during this process, generating mutations that can give rise to cancer. To avoid ...
Cell & Microbiology
May 20, 2015
0
25
ASU scientists, together with collaborators from the Chinese Academy of Sciences in Shanghai, have published today, in Nature Structural and Molecular Biology, a first of its kind atomic level look at the enzyme telomerase ...
Cell & Microbiology
May 4, 2014
1
0
The cure for cancer comes down to this: video games.
Biochemistry
Feb 16, 2012
0
0
