The Molecular Virology Research Group at Pompeu Fabra University (UPF), in collaboration with the Epitranscriptomics and RNA Dynamics group of the Center for Genomic Regulation (CRG), has discovered a new mechanism whereby ...
Cell & Microbiology
Aug 29, 2022
0
84
A new method allows researchers to determine the structure and abundance of "transfer RNAs" (tRNA)—small, highly structured and chemically modified RNAs involved in protein production—in living cells. Misfolding of tRNAs ...
Molecular & Computational biology
Jun 28, 2022
0
44
A new study led by researchers at University of Utah Health details a novel mechanism that infectious bacteria use to quickly adjust to environmental stress. The discovery could help explain why certain types of common infections—such ...
Cell & Microbiology
Mar 23, 2022
0
49
Mutations in genes encoding mitochondrial aminoacyl-tRNA synthetases are linked to diverse diseases. However, the precise mechanisms by which these mutations affect mitochondrial function and disease development are not fully ...
Molecular & Computational biology
Jan 3, 2022
0
11
The chemical steps in an important cellular modification process that adds a chemical tag to some RNAs have been revealed in a new study. Interfering with this process in humans can lead to neuronal diseases, diabetes, and ...
Molecular & Computational biology
Sep 15, 2021
0
341
Birds have been shaped by evolution in many ways that have made them distinct from their vertebrate cousins. Over millions of years of evolution, our feathered friends have taken to the skies, accompanied by unique changes ...
Evolution
Apr 14, 2021
0
3
A Ludwig-Maximilians-Universitaet (LMU) in Munich team has shown that slight alterations in transfer-RNA molecules (tRNAs) allow them to self-assemble into a functional unit that can replicate information exponentially. tRNAs ...
Evolution
Mar 2, 2021
1
25
Transfer RNAs (tRNAs) deliver specific amino acids to ribosomes during translation of messenger RNA into proteins. The abundance of tRNAs can therefore have a profound impact on cell physiology, but measuring the amount of ...
Biotechnology
Mar 1, 2021
0
92
In cells, transfer RNA (tRNA) translates genetic information from the encoding messenger RNA (mRNA) for protein synthesis. New results from ultrafast spectroscopy and in-depth theoretical calculations demonstrate that the ...
Molecular & Computational biology
Dec 9, 2020
0
4
Translation is the process by which genetic information is converted into proteins, the workhorses of the cell. Small molecules called transfer RNAs (tRNAs) play a crucial role in translation; they are the adapter molecules ...
Cell & Microbiology
Nov 3, 2020
0
13
