New way to see RNA could help fight pathogens
In genetics, DNA has always been the star of the show, but scientists are now uncovering the crucial roles of a lesser-known player: transfer RNA.
In genetics, DNA has always been the star of the show, but scientists are now uncovering the crucial roles of a lesser-known player: transfer RNA.
Biochemistry
Jul 2, 2020
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213
The stages in which ribosomes synthesize life-sustaining proteins have been revealed in unprecedented real-time detail by UMass Medical School structural biologists Andrei Korostelev, Ph.D., and Anna Loveland, Ph.D. Their ...
Molecular & Computational biology
Jul 2, 2020
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16
In cells, protein is synthesized based on the genetic code. Each protein is coded by the triplet combination of chemicals called nucleotides, and a continuous reading of any set of triplet codes will, after a multi-step process, ...
Molecular & Computational biology
May 27, 2020
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3
Defects in tRNA biogenesis influence gene expression and are associated with many types of human diseases, such as cancer and neurological diseases. In his thesis, Fu Xu contributes to new knowledge about the factors that ...
Molecular & Computational biology
Jan 16, 2020
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4
Cornell researchers have uncovered the structure of a regulatory mechanism unique to bacteria, opening the door for designing new antibiotics targeted to pathogens.
Biochemistry
Nov 18, 2019
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230
A molecule called tRNA, or transfer ribonucleic acid, is an essential component of the human genome that acts as a translator. It reads the genetic code and translates it into proteins—one of the key building blocks of ...
Biotechnology
Aug 13, 2019
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93
Antibiotic resistance is a major health threat, with about two million people in the US getting an antibiotic-resistant infection per year, according to the Centers for Disease Control and Prevention (CDC). Gram negative ...
Cell & Microbiology
Apr 30, 2019
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398
Nonsense mutations are single-letter errors in the genetic code that prematurely halt the production of critical proteins. These unfinished proteins are unable to function normally, and nonsense mutations cause 10-15 percent ...
Molecular & Computational biology
Feb 19, 2019
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45
Why do distinct species have different proteins? Is there a key that allows eukaryotic cells to produce proteins involved in multicellularity that are mostly absent in prokaryotes? These are some of the questions addressed ...
Cell & Microbiology
Jan 14, 2019
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5
Researchers from the University of Chicago have developed a high-throughput RNA sequencing strategy to study the activity of the gut microbiome.
Cell & Microbiology
Dec 17, 2018
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133