Northwestern Medicine investigators developed a technique to catalog how cells dispose of unnecessary proteins, a process that has implications for cancer and autism-spectrum diseases, according to findings published in Nature ...
Biochemistry
Jan 11, 2018
0
28
Gene editing has begun to be tested in clinical trials, using CRISPR-Cas9 and other technologies to directly edit DNA inside people's cells, and multiple trials are recruiting or in the planning stages. A new study led by ...
Biotechnology
Dec 11, 2017
0
104
The more than 200 different types of human cells have the same DNA but express different ensembles of genes. Each cell type was derived from embryonic stem cells, which are called pluripotent stem cells because they can differentiate ...
Cell & Microbiology
Nov 15, 2017
0
97
Nanotechnology, the science of developing materials containing very small fibers, is having a growing influence on daily life. Now researchers have shown for the first time in mice that long and thin nanomaterials called ...
Bio & Medicine
Nov 6, 2017
1
1073
Ishan Deshpande and his colleagues from the group of Susan Gasser and the Protein Structure Facility at the FMI elucidated the mechanism of how Mec1-Ddc2, a tumor suppressor involved in DNA damage response assembles at sites ...
Cell & Microbiology
Oct 16, 2017
0
68
For several years, scientists have known that SIRT6 – one of seven sirtuins, a family of mammalian proteins with important biological functions, including promoting longer, healthier life – is a tumor suppressor. It has ...
Biochemistry
May 11, 2017
0
4
A new method combining tumor suppressor protein p53 and biomineralization peptide BMPep successfully created hexagonal silver nanoplates, suggesting an efficient strategy for controlling the nanostructure of inorganic materials.
Nanophysics
May 3, 2017
0
207
Northwestern Medicine scientists have revealed the role amino-terminal methylation plays in a specific protein in the centromere, a region of the chromosome important in cell division, and how the dysregulation of this protein ...
Biochemistry
Apr 19, 2017
0
9
Scientists at the University of Würzburg have generated new insights into the intricate molecular underpinnings of ubiquitin signaling. Their results may provide new avenues for cancer therapy.
Cell & Microbiology
Feb 14, 2017
0
6
Two studies publishing on 1st September in Open Access journal PLOS Biology identify overlapping groups of cells in the Drosophila larva that have unique properties. In one case, the cells are resistant to irradiation or ...
Cell & Microbiology
Sep 1, 2016
0
8
