Related topics: stem cells , proceedings of the national academy of sciences , mice , cancer , bone marrow
News tagged with mouse model
Mice regain ability to extend telomeres suggesting potential for dyskeratosis congenita therapy
Oct 19, 2009 |
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The human genetic disease dyskeratosis congenita (DKC) is an autosomal dominant disease that leads to abnormalities in tissues with a rapid cell turnover - the skin, nails, bone marrow, lungs and gut. Patients with DKC experience ...
The Nobel Prize and Pond Scum as a 'Model' Organism
Oct 15, 2009 |
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A man is a man and a mouse is a mouse, but if you talk to a few biomedical scientists about their research, at least one is likely to spring the term “mouse model” on you.
Loss of tumor supressor gene essential to transforming benign nerve tumors into cancers
Oct 13, 2009 |
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Researchers at UCLA's Jonsson Comprehensive Cancer Center showed for the first time that the loss or decreased expression of the tumor suppressor gene PTEN plays a central role in the malignant transformation of benign nerve ...
Scientists encouraged by new mouse model's similarities to human ALS
Oct 12, 2009 |
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A new mouse model of amyotrophic lateral sclerosis (ALS) closely resembles humans with the paralyzing disorder, researchers at Washington University School of Medicine in St. Louis report.
New study pinpoints gene controlling number of brain cells (w/ Video)
Medicine & Health / Neuroscience
Oct 04, 2009 |
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In populating the growing brain, neural stem cells must strike a delicate balance between two key processes - proliferation, in which the cells multiply to provide plenty of starting materials - and differentiation, in which ...
Researchers identify gene with possible link to infertility in mice
Oct 02, 2009 |
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Virginia Commonwealth University researchers have identified the role of a gene in regulating molecular signals involved with ovarian follicle development, which may one day help shed light on some of the causes of fertility ...
Drug That Crosses Blood-Brain Barrier Reduces Formation of Brain Metastases in Mice
Sep 29, 2009 |
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(PhysOrg.com) -- The drug vorinostat is able to cross the blood-brain barrier and reduce the development of large metastatic tumors in mice brains by 62 percent when compared to mice that did not receive the drug, according ...
Social isolation worsens cancer
Sep 29, 2009 |
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Using mice as a model to study human breast cancer, researchers have demonstrated that a negative social environment (in this case, isolation) causes increased tumor growth. The work shows -- for the first time -- that social ...
Research isolates liver cancer stem cells prior to tumor formation
Sep 17, 2009 |
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Penn State College of Medicine researchers, in collaboration with colleagues at the University of Southern California, have taken an important step in understanding the role of stem cells in development of liver cancer. Using ...
Rare genetic disease successfully reversed using stem cell transplantation
Sep 17, 2009 |
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A recent study by Scripps Research Institute scientists offers good news for families of children afflicted with the rare genetic disorder, cystinosis. In research that holds out hope for one day developing a potential therapy ...
Gene variation that lets people get by on fewer zees transferred to create insomniac mice
Sep 16, 2009 |
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A University of Utah sleep expert has joined with researchers at the University of California, San Francisco (UCSF), and Stanford University to identify a genetic variation in humans, which the scientists also developed in ...
Researchers discover the first-ever link between intelligence and curiosity
Medicine & Health / Neuroscience
Sep 14, 2009 |
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(PhysOrg.com) -- Scientists from University of Toronto and the Samuel Lunenfeld Research Institute of Mount Sinai Hospital have discovered a molecular link between intelligence and curiosity, which may lead to the development ...
Master gene that switches on disease-fighting cells identified by scientists
Sep 13, 2009 |
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(PhysOrg.com) -- The master gene that causes blood stem cells to turn into disease-fighting 'Natural Killer' (NK) immune cells has been identified by scientists, in a study published in Nature Immunology today. ...
Researchers discover therapeutic target that could help patients with pulmonary fibrosis
Aug 23, 2009 |
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A diagnosis of Idiopathic Pulmonary Fibrosis is not much better than a death sentence: there is no treatment and the survival rate is less than three years.
Gene discovery reveals a critical protein's function in hearing
Aug 21, 2009 |
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Discovery of a deafness-causing gene defect in mice has helped identify a new protein that protects sensory cells in the ear, according to a study led by University of Iowa researchers. The findings, which ...
